The single-domain antibody is one of the smallest units of the antibodies antigen-binding. The single-domain antibody consists of either only one variable domain or one constant engineered domain that completely enables the binding of the target. The single-domain antibody obtained from naturally occurring variable domains which are derived from sharks and camelids. The single-domain antibodies can also be obtained from the engineered human variable or from constant antibody domains of the light or heavy chain. The single-domain antibody molecules developed as a promising field for biomedical applications. This is because of the single-domain antibody that has high affinity, specificity, and stability. The single-domain antibody is also small in size and it has the advantage of multiple re-formatting opportunities. The single-domain antibody platforms have an outstanding ability of penetration which is able to pass through the blood-brain barrier. These advantages of single-domain antibody platforms are expected to boost the growth of single-domain antibody platforms market.
Particularly, a single-domain antibody platforms combines the advantages of conventional antibodies with main small molecule drugs features. Single-domain antibody platforms has single-chain peptide and due to its simple nature, single-domain antibody platforms has a unique drug format flexibility which allows effective drug development and discovery. Some of the entities in this field has already proven to be successful in clinical development. Additionally, the single-domain antibodies can exist in extreme conditions and it has high stability to function. There has been a rise in the demand for drug development due to an increasing number of disorders and diseases, worldwide. These factors act as the main driving factors to boost the growth of single-domain antibody platforms market.
The global market for single-domain antibody platforms is segmented on basis of applications, end user and geography.
Single-domain antibody platforms are considered to be one of the fastest developing fields in the market. The rising stats of diseases worldwide are the key factor to increase the interest of researchers in the biomedical and single-domain antibody platforms fields. The single-domain antibody platforms recognize the novel epitopes which regular size of antibodies unable to find. The single-domain antibody platforms improve the bioavailability for pharmaceutical applications. The single-domain antibody platforms have great potential in downstream engineering. The single-domain antibody platforms can be expressed in both eukaryotic and prokaryotic systems. All these factors are boosting the growth of single-domain antibody platforms market. However, the low availability of resources and facilities and lack of expertise in the research field may hamper the growth of global single-domain antibody platforms market. Also, low research and development funding can affect the single-domain antibody platforms market growth.
The single-domain antibody platforms market in North America will dominate the global single-domain antibody platforms market due to advanced infrastructure, technological advancement and high spending in research and development activities. The single-domain antibody platforms market in the Asia Pacific region will show high CAGR growth and is estimated to be a lucrative market for new emerging players in the single-domain antibody platforms market due to developing infrastructure and growing spending. The market for single-domain antibody platforms in Latin America and the Middle East and Africa regions are expected to show a constant growth over the forecast period due to raising awareness and funding for research and development.
Some of the key players in the single-domain antibody platforms market include Creative-Biolabs, BioPharmGuy, Jubilant Life Sciences, Tcg Lifesciences, Piramal Life Sciences, Eurofins Scientific, Siemens AG, Elsevier (RELX plc), Pharmaceutical Product Development, LLC, Laboratory Corporation and others.
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