Professionals 244 Users Online

Cervical Total Disc Replacement Market

Rising incidence of cervical degenerative diseases is the factor fostering the Cervical Total Disc Replacement Market growth

Cervical Total Disc Replacement Market by Type (Metal on a Biocompatible Material (M-o-B) and Metal on Metal (M-o-M))

Cervical Total Disc Replacement Market Outlook (2023 to 2033)

The global revenue from Cervical Total Disc Replacement Market was around US$ 486.6 Million in 2022, with the global market expected to grow at a CAGR of 12.2% to reach a valuation of around US$ 1.7 Billion by the end of 2033.

Market Size (2023)

US$ 545.7 Million

Projected Market Value (2033)

US$ 1.7 Billion

Global Market Growth Rate (2023 to 2033)

12.2% CAGR

Market Share of Top 5 Countries


As assessed by Persistence Market Research, metal on metal held a market share of around 85.8% in the global market, in 2022. Overall, cervical total disc replacement market sales account for around 1.18% of revenue share in the global orthopaedic market, which was valued at around US$ 41.1 Billion in 2022.

Sample Report

FREE Report Sample is Available

In-depth report coverage is now just a few seconds away

Download PDF Get FREE Report Sample

Sales Analysis of Global Market from 2014 to 2022 Vs Market Outlook for 2023 to 2033

The global market recorded a historic CAGR of 10.4% in the last 8 years from 2014 to 2022.

The cervical spine is composed of seven bones, referred to as cervical vertebrae, which are stacked on top of one another to form the neck region. Cervical discs provides cushioning between the cervical vertebrae, also working as shock absorbers. Additionally, the upper portion of spinal cord passes via a tunnel formed by cervical spine that is safe. The spinal nerves that supply movement and sensation to upper body are located in this region of spinal cord.

A portion of vertebrae or cervical disc, sometimes, presses on spinal cord or spinal nerves when the space between vertebrae is too small, resulting in discomfort, numbness, or weakness. Disk surgery may be advised if these symptoms do not improve with nonsurgical treatments.

An unhealthy cervical disc is removed during cervical disc replacement surgery, and a synthetic disc is put in its place. The problematic disc is removed before this treatment is available, and the vertebrae above and below are fused to stop mobility.

Using an artificial cervical disc in place of natural one is a novel treatment that was authorised by the FDA. Compared to standard cervical disc surgery, disc replacement surgery may provide with more mobility and put less strain on remaining vertebrae.

Neck pain, neck stiffness, headache, pain that travels into shoulders or into arms, numbness, and weakness of shoulders are some of the common symptoms of cervical total disc replacement surgery.

The global market is likely to show high growth over the coming years at a CAGR of 12.2% and reach a global market size of US$ 1.7 Billion by 2033.

Custom Report Cover

Make This Report Your Own

Take Advantage of Intelligence Tailored to your Business Objective

> Get a Customized Version

How Can the Global Market Grow?

“Increasing Incidence of Degenerative Disc Issues”

Global elderly population rise and the rising prevalence of degenerative disc problems are the two main drivers propelling the global cervical total disc replacement devices market.

  • Cervical radiculopathy (radiating pain from cervical disc degeneration), in which a compressed nerve causes pain, numbness, or weakness in the neck and surrounding areas, has an annual incidence of 107 per 100,000 men and 64 per 100,000 women in the U.S., according to data presented by the American Academy of Orthopedic Surgeons in 2017.

Regular product approvals are yet another important feature fostering market expansion.

  • For instance, AxioMed LLC's Cervical Freedom Total Disc Replacement was granted CE mark clearance in March 2019. Additionally, Medtronic's Prestige LP cervical disc was approved by U.S.FDA in July 2017. The product was designed for the treatment of cervical disc degeneration/disease that causes nerve or spinal cord compression at C3-C7 portions of the neck.

The Prestige LP disc is the third artificial cervical disc from Medtronic to have undergone clinical testing, and it is the first to have been found to be both safe and effective for one- and two-level treatments.

Market Research Methodology

Market Research Methodology

-Perfect through Years of Diligence

Check Research Methodology

Can the Market Growth Be Affected in Any Way?

“Lack of Clinical Data Supporting Superiority Compared to ACDF.”

The cervical total disc replacement market is difficult to expand due to a lack of convincing evidence comparing anterior cervical discectomy fusion versus cervical whole disc replacement. Clinical proof demonstrating the benefits of cervical disc replacement devices over traditional methods and techniques will raise awareness among patients and surgeons and promote adoption of these devices, which will propel market expansion.

The growth of the cervical total disc replacement device market is anticipated to be hampered in the near future by the high cost associated with cervical whole disc replacement, which comprises artificial disc replacement procedures and spinal fusion surgeries.

  • For instance, the typical cost of a particular disc replacement surgery operation varies among U.S. states from $16,000 to $46,000.

Alternative treatments for cervical disc degenerative disease include physiotherapy and specialised workouts, which is predicted to restrain the growth of the cervical complete disc replacement device market over the forecast period.

Physiotherapy is the most popular first-line treatment for degenerative disc diseases, such as cervical disc degeneration and other spine degeneration disorders, among the ageing population, according to research published in the Toronto Physiotherapy Journal in January 2014.

Sales Team

Sales Team
Client Partner

Let's Connect

Connect me to identify winning opportunities

Ask An Expert
I'm Available

Country-wise Insights

Why is the United States Market Booming?

“Increasing Approvals by FDA”

The United States accounted for around 94.4% market share in the North America market in 2022. New product innovation with FDA approval are the factors fostering the regional dominance.

  • For instance, according to article published in 2021, in Elsevier Inc., in 2007, the United States Food and Drug Administration (FDA) granted the cervical total disc replacement (CTDR) procedure its first FDA approval. Since then, the FDA has approved 8 additional artificial discs for single-level CTDR. Additionally, two of these have received approval for 2-level CTDR.

For symptomatic patients with radiculopathy or myelopathy brought on by disc herniation or spondylosis and refractory to conservative therapy, all devices are appropriate for levels C3 to C7. Studies have demonstrated that CTDR is noninferior to anterior cervical decompression and fusion in terms of overall success. This continuous launches and approval are responsible for the regional dominance.

Will Germany Be a Lucrative Market for Cervical Total Disc Replacement?

“Increasing Surgical Procedures”

The Germany market held around 19.4% market share of the Europe market in 2022. The regional dominance is attributed to a high rate of ageing and the frequency of spinal disorders, which has led to an increase in the number of disc replacement surgeries.

  • According to the Federal Statistical Office, Germany performed 17.2 million surgical procedures in 2019.

Among them, hip implant procedures, endoscopic surgeries, intestinal surgeries, and spinal surgeries were some of the most frequent. This boosted the region's portion.

How is China Emerging as a Prominent Market?

“Growing Geriatric Population”

China held a market share of about 52.5% of the East Asia market in 2022. One of the key elements fuelling the expansion of the regional market is the growing pool of elderly people. Growth in the market is further supported by ongoing increases in the standard of living and overall life expectancy, which are related to advancements in medical facilities and rising disposable income levels.

A sizeable section of the subpopulation that is susceptible to various diseases and disorders, such as degenerative spine diseases, includes the geriatric population pool, which in turn increases the demand for the product.

Category-wise Insights

Which Disc is Driving Demand within the Global Market?

“Increasing Sports Related Injuries”

The metal on metal disc held around 85.8% share of the total market in 2022. Extensive literature and clinical trials have been performed to understand the impact of Metal-on-metal articulating bearing surfaces and provide dominating stance of this segment.

In United States, there are numerous cervical TDR implants which has received FDA approval certifications. These implants feature prosthetic endplates made up of metal alloys while articulating via central core of polymer. Additionally, the market is growing due to the high overall success rate of metal-polymer artificial disc replacement procedures. Additionally, the market is anticipated to grow as more people suffer trauma- and sports-related injuries and have orthopaedic procedures.

  • The NFL Physicians Society estimates that around 1.2 million injuries happening each year is football-related. The market is anticipated to rise as a result of advancements in technology on a global scale and an increase in the number of older people.

Which Design is Widely Adopted for the Production of Cervical Total Disc Replacement?

“Growing Advantages of Semi Constrained Discs”

Semi constrained discs held the dominant share in the global market and is further expected to grow at 13.7% CAGR between 2023 and 2033. Semi-constrained discs provide the advantages of unrestricted movement with higher stability, even during excessive motion.

Implants can also vary in terms of their endplate surface (spikes, keels, screws or porous coating), material composition (cobalt, stainless steel, or titanium), or method of articulation (saddle versus ball-and-socket). This affirmatory factors are responsible for segment dominance.

Which Material is Widely Adopted for the Production of Cervical Total Disc Replacement?

“Growing Adoption of Mobi C Cervical Disc”

Cobalt chromium held around 43.7% share of the total market in 2022. Growing awareness and increasing adoption of Mobi C cervical disc for replacement surgery is the primary reason driving the segment growth. The Mobi-C cervical disc's dynamic polyethylene bearing that adapts to cervical spine movement is one of its distinctive features. Two endplates made of cobalt-chromium-molybdenum metal alloy, which are themselves coated in titanium and hydroxyapatite, support this bearing (a bone-like material).

The central bearing has a theoretical risk of displacement but offers remarkable joint mobility. Hydroxyapatite may speed up and improve the stability of an artificial device's integration with bone.

Which End User Propels the Global Sales in the Market?

“Presence of Advanced Implants in Hospitals”

The hospitals segment held a share of about 45.6% in 2022, within the global market. Numerous resources and cutting-edge implants for the treatment and diagnosis of cervical spine problems are found in hospital settings, which can be ascribed to the segment expansion.

Another driver boosting the segment's growth over the projection period is the rising demand for prosthesis for patients with myelopathy, radiculopathy, and severe neck discomfort. Also, hospitals treat patients better and have qualified medical staff, which pulls in a large number of patients.

Competition Landscape

Consistent research and development and conducting clinical trails to device new products are the key factors driving the global market. Leading industry players are actively involved in conducting such activities to maintain their foothold in the market.

Some key instances of development include :

  • In September 2019, The Institute for Biomechanics, Switzerland, proposed a procedure for regulated epigallocatechin 3-gallate administration for the degenerative intervertebral disc
  • In July 2019, Centinel Spine LLC obtained U.S. FDA experimental device approval to launch a two-level clinical trial for the Prodisc C anterior cervical complete disc device.

Similarly, the team at Persistence Market Research has tracked recent developments related to companies in the cervical total disc replacement market, which are available in the full report.

Cervical Total Disc Replacement Industry Report Scope



Forecast Period

2023 to 2033

Historical Data Available for

2014 to 2022

Market Analysis

  • USD Million for Value
  • Units for Volume

Key Countries Covered

  • United States
  • Canada
  • Brazil
  • Argentina
  • Mexico
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • India
  • Thailand
  • Malaysia
  • Indonesia
  • China
  • Japan
  • South Korea
  • Australia
  • New Zealand
  • Türkiye
  • GCC
  • North Africa
  • South Africa

Key Market Segments Covered

  • Disc Type
  • Design
  • Material
  • End User
  • Region

Key Companies Covered

  • LDR Holdings
  • Johnson and Johnson
  • Medtronic
  • Globus Medical, Inc.
  • NuVasive Inc.
  • Stryker Corporation
  • Orthofix Medical Inc.
  • Centinel Spine, Inc.
  • FH Orthopedics S. A. S.
  • Zimmer Biomet Holdings, Inc
  • Spine Innovations
  • AxioMed LLC

Report Coverage

  • Market Forecast
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives

Customization & Pricing

Available upon Request

Key Segments Covered in Cervical Total Disc Replacement Industry Research

Disc Type:

  • Metal on a Biocompatible Material (M-o-B)
  • Metal on Metal (M-o-M)


  • Constrained Discs
  • Semi Constrained Discs
  • Unconstrained Discs


  • Cobalt Chromium
  • Titanium
  • Ceramic
  • Others

End User:

  • Hospitals
  • Orthopaedic Clinics
  • Ambulatory Surgical Centres


  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East and Africa

- Companies Covered in This Report -

  • LDR Holdings
  • Johnson and Johnson
  • Medtronic
  • Globus Medical, Inc.
  • NuVasive Inc.
  • Stryker Corporation
  • Orthofix Medical Inc.
  • Centinel Spine, Inc.
  • FH Orthopedics S. A. S.
  • Zimmer Biomet Holdings, Inc
  • Spine Innovations
  • AxioMed LLC

- Frequently Asked Questions -

The global market is currently valued at around US$ 486.6 Million in 2022.

The global market estimates for 2023 is around US$ 545.9 Million in 2023.

The global market will be valued at around US$ 1.7 Billion by the end of 2033.

Sales of the market are set to witness growth at a CAGR of 12.2% between 2023 and 2033.

Demand for the global market increased at a 10.4% CAGR from 2014 to 2022.

The U.S., Germany, Italy, France, and the U.K., account for most demand within the market, currently holding around 73.1% market share.

The U.S. accounts for around 94.4% share of the North American market in 2022.

The China market held a share of about 52.5% in the East Asia cervical total disc replacement market in 2022.

The Germany market held around 19.4% market share of the Europe market in 2022.

LDR Holdings, Johnson and Johnson, Medtronic, Globus Medical, Inc., NuVasive Inc., Stryker Corporation, Orthofix Medical Inc., Centinel Spine, Inc., FH Orthopedics S. A. S., Zimmer Biomet Holding, Inc., Spine Innovations and AxioMed LLC are the key players driving the global market.

This site uses cookies, including third-party cookies, that help us to provide and improve our services. Privacy Policy
Google translate