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Glycobiology Market

The Rising Prevalence of Infectious Diseases across the Globe Are Driving the Demand within the Glycobiology Market

Glycobiology Market by Product (Instruments, Enzymes, Consumables, Kits and Reagents)

Glycobiology Market Outlook (2023 to 2033)

The global revenue from the Glycobiology Market was about US$ 1.3 Billion in 2022, with the global market expected to grow at a CAGR of 15.5% to reach a valuation of around US$ 6.2 Billion by the end of 2033.

Market Size (2023)

US$ 1.5 Billion

Projected Market Value (2033)

US$ 6.2 Billion

Global Market Growth Rate (2023 to 2033)

15.5% CAGR

Market Share of Top 5 Countries

62.8%

As assessed by Persistence Market Research, enzyme held a market share of around 55.3% in the global market, in 2022. Overall, glycobiology market sales account for approximately 11.5% of revenue share in the global enzymes market, which was valued at around US$ 11.2 Billion in 2022.

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Sales Analysis of Market from 2015 to 2022 Vs Market Outlook for 2023 to 2033

The global market recorded a historic CAGR of 15.5% in the last 7 years from 2015 to 2022.

Glycobiology is the study of glycans, which are another name for carbohydrates. Glycans are present in all living things. Glycobiology is a fast developing branch of biology with applications in biotechnology, healthcare, and fundamental study. Most proteins in eukaryotic cells undergo post-translational modification. The binding of glycans, or "glycosylation," is one of the most prevalent changes that is necessary for cell survival. Glycosylation can be N-linked or O-linked, with the former including an asparagine (the glycan is attached to a serine or threonine).

Glycans are varied, complicated molecules, and their specific structures dictate how they perform various biological tasks. To correctly reveal glycan structure, which may subsequently be connected to a particular function, effective enzymatic tools and analytical techniques are needed. The sticky qualities of proteins and cells are determined by glycosylation. The fact that the immune system relies heavily on interactions between glycans and proteins to operate emphasizes the significance of glycans in physiology, pathogen identification, cancer, and autoimmune disorders.

Several other processes, such as transportation, metabolic and gene regulation, protein activity, protein clearance, and tissue development are all regulated by glycan molecules. Because glycans are so important in immunological interactions, glycoproteins and carbohydrates are currently the focus of next-generation therapies, vaccines, and diagnostics.

Increasing HIV infection rates, rising government financing, and R&D activities will all help fuel growth since R&D produces newer, more advanced, or inventive products, which will boost sales. The need for technologically improved products from end users such research labs, academic institutions, and biotechnology & pharmaceuticals companies to investigate carbohydrate molecules is also anticipated to fuel growth of the worldwide glycobiology market.

The global market is likely to show high growth over the coming years at a CAGR of 15.5% and reach a global market size of US$ 6.2 Billion by 2033.

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How Can the Global Market Grow?

Increasing Prevalence of Infectious Diseases

The demand for glycobiologic enzymes is anticipated to rise as vaccinations to prevent extremely contagious viral diseases, such as avian influenza, has become more popular. Governments have stocked up on Tamiflu due to concern over the spread of such an infection. Glycobiologic proteins known as glycosidase and its glycan substrate are two of Tamiflu's primary ingredients. They effectively aid in preventing the two primary surface proteins known to cause influenza, neuraminidase and hemagglutinin.

These elements may increase demand for glycobiologic enzymes from larger drug producers and government-sponsored drug manufacturing facilities, which are crucial suppliers to numerous governments across the globe.

Glycobiology is increasingly being used to treat degenerative diseases including rheumatoid arthritis, which is a key driver of market growth.

  • Applications of glycobiology are primarily observed in the recombinant monoclonal antibodies therapeutic class (rMAbs). These therapeutic glycoproteins are frequently used into pharmaceutical formulations to treat autoimmune diseases like rheumatoid arthritis and multiple sclerosis. TNF-inhibiting recombinant monoclonal antibodies are employed to stop the activity of this protein.

Further, it is anticipated that developments in chemical synthesis and bioengineering would produce more conclusive documented data, which may increase demand for glycobiologic enzymes over the study period.

Companies that manufacture technologies for structural analysis of carbohydrate molecules have a wide range of products to expand their clients and give customers a variety of options based on their research frameworks.

  • For instance, the Impact II, MaXis II ETD, AmaZon speed Ion Trap Sets, AmaZon speed ETD, amaZon SL, SolariX XR, UltrafleXtreme MALDI-TOF/TOF, and Autoflex are all manufactured by Bruker Corporation, a major supplier of mass spectrometer instruments worldwide.

Triple Quadrapole (TQS), Ion Trap, and Hybrid System (LS/MS/MS) mass spectrometers are made by Thermo Fisher Scientific, Inc. Companies are concentrating on ongoing technological advancement to introduce new products to fulfil end-user requirements, which is boosting the worldwide glycobiology market's revenue growth.

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Can the Market Growth Be Affected in Any Way?

“Lack of Qualified Specialists”

In comparison to DNA or protein studies, which necessitate qualified professionals to carry out the protocol, glycobiology research entails a variety of complexity. Despite the fact that glycan research began in the 18th century, there aren't enough highly trained professionals to carry out the process with little to no error. Since its inception, glycobiology has seen numerous technological developments and has found extensive use in a number of industries, including drug discovery, treatments, and diagnostics.

There are not many specialists with the necessary training, nevertheless, to execute the process well. To achieve the intended results with the least amount of manual error, the protocol is detailed and calls for a skilled professional to carry out the procedure. During the projected period, a lack of skilled labor is anticipated to restrain the growth of the glycobiology market globally.

The issue impeding the growth of the global glycobiology market is the imprecision in measuring the overall structure of glycans due to variations in the responsiveness to hydrolysis of various bonds, variations in the degradation of particular saccharides, or a lack of specificity or sensitivity in the assay, such as the immunotherapy test.

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Country-wise Insights

Why is the U.S. Market Booming?

“Presence of Numerous Market Players”

The U.S. accounted for around 88.3% market share in the North America market in 2022. As major pharmaceutical and biopharmaceutical companies like Danaher, Agilent Technologies, Merck KGaA and Thermo Fisher Scientific are present. The regional market has been pushed by the presence of well-established healthcare infrastructure and accessibility to cutting-edge products. Government support for R&D initiatives is yet another important element driving the development of the glycobiology market in this region.

  • Vector Laboratories, a leader in cutting-edge proteomic and glycobiology solutions, launched Glysite Scout Glycan Screening Kits, in March 2022. These kits are fully integrated for the recognition of glycan expression in tissue sections and enable the profiling and characterisation of complex glycans in biological systems.

Glycan research is becoming more and more popular as more academics show an interest in it because of the potential impact it may have on significant areas of medical research like oncology. As a result of the aforementioned factors, the market under study is anticipated to grow rapidly over the coming years.

Will the U.K. Be a Lucrative Market for Glycobiology?

“Utilization of Advanced Techniques for Research”

The U.K. market held around 15.5% market share of the Europe market in 2022. New methods such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry are quickly replacing traditional techniques like gel electrophoresis and elemental analysis for the characterization of glycoforms in complex glycoproteins.

  • NMR is proving to be superior to MS for analyzing the structure of complex glycans because MS simply serves to confirm the expected product of glycan synthesis and does not provide true structural information.

In order to understand the structure of a microorganism's cell surface polysaccharide, which is utilized as a probiotic in bowl disease, researchers at the University of Huddersfield in the United Kingdom are using NMR.

How is China Emerging as a Prominent Market?

“Increasing Government Research & Development Expenditure”

China held a market share of about 4.5% of the global market in 2022. Several governments in Asia Pacific regions are taking action to solve the region's shortage of competent individuals in the field of glycoscience by funding basic research projects.

  • For instance, The National High-Tech R&D Program and National Basic Research Program of China are dedicated to research and advancements in the fields of biotechnology, information technology, and the life sciences.

Category-wise Insights

Which Product is Driving Demand within the Global Market?

“Crucial Role of Enzymes in Glycobiology”

The enzyme segment held around 55.3% share of the total market in 2022. In glycobiology, enzymes play a number of important roles. For instance, transferases contribute to the production of complex carbohydrates. Additionally, glycosidases and other enzymes, such as sulfatases, modify and metabolize carbohydrates.

These enzymes can therefore be used as helpful tools to comprehend the structure and function of carbohydrates. They could be used, for instance, to define or ascertain the structure of an interesting oligosaccharide or to alter the structure of a carbohydrate to examine how it affects biological processes.

Which Enzyme is Widely Adopted for the Production of Glycobiology?

“Growing Adoption of Galactosidases”

Galactosidases held around 27.6% share of the total market in 2022. Over the projection period, increasing galactosidases adoption by a variety of end users, primarily biotechnology companies and food and beverage industries to improve the solubility, sweetness, digestibility, and flavor of dairy products is anticipated to support the segment's revenue growth.

Which Application is Driving Demand within the Global Market?

“Utilization of Glycan in Vaccine Development”

The drug discovery and development held around 54.7% share of the total market in 2022. The demand for discovery drug development is rising along with the burden of chronic diseases. Glycans are crucial for biological activities including cell-cell communication and are therefore crucial for the creation of new drugs. As a result, glycan chains are altered to create drug syntheses. For instance, hyaluronan, a naturally occurring glycosaminoglycan disaccharide unit, has several uses in medicine. It is crucial for treating osteoarthritis as well as post-surgical wounds.

  • Glycan nanostructures are seen as prospective targets for molecular diagnosis, antiviral treatments, and vaccine development.

With the aid of genetic engineering techniques and glycoprotein expression systems, self-adjuvanted vaccines based on glycans can be developed to enhance immunogenicity and vaccine response. Glycobiology is therefore crucial to the creation of vaccines, fostering the sector's expansion.

Which End User Propels the Global Sales in the Market?

“Increasing Company collaborations and Acquisition”

The biopharmaceutical companies segment held a share of about 26.5% in 2022, within the global market. An important development in the global glycobiology market is the formation of partnerships between manufacturers of enzymes and those of instruments in order to broaden the consumer base. There are just a few companies that produce both enzymes and equipment for studying carbohydrates, and the worldwide glycobiology market is competitive.

Companies are concentrating on growing their market share through collaborations with significant industry players across a variety of regions to offer end consumers high-quality products and receive precise research results.

Competition Landscape

The key players are driving market growth while adopting growth strategies like collaborations and co-marketing agreements to provide their product to the masses at regional level. Companies are also leveraging social media and digital ads to inform consumers about the availability of their newest products.

Some key instances of development include:

  • In June 2022, Thermo Fisher Scientific and TransMIT GmbH Center for Mass Spectrometric Developments announced a co-marketing agreement to increase the use of a mass spectrometry imaging (MSI) platform for spatial multi-omics uses in pharma and clinical labs.
  • In April 2022, Using unbiased lipidomics, glycomics, and metabolomics tissue imaging in conjunction with AmberGen's HiPLEX-IHC peptide code antibody probes, Bruker introduced a unique MALDI HiPLEX-IHC tissue imaging solution for timsTOF flex.

Similarly, the team at Persistence Market Research has tracked recent developments related to companies in the glycobiology market, which are available in the full report.

Glycobiology Industry Report Scope

Attribute

Details

Forecast Period

2023 to 2033

Historical Data Available for

2015 to 2022

Market Analysis

USD Million for Value

Key Countries Covered

  • United States
  • Canada
  • Brazil
  • Argentina
  • Mexico
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • BENELUX
  • Nordics Countries
  • India
  • Thailand
  • Malaysia
  • Indonesia
  • China
  • Japan
  • South Korea
  • Australia
  • New Zealand
  • Türkiye
  • GCC Countries
  • North Africa
  • South Africa

Key Market Segments Covered

  • Product
  • Enzyme
  • Application
  • End User
  • Region

Key Companies Covered

  • Glycodiag
  • Tracxn Technologies Limited
  • Agilent Technologies, Inc.
  • Takara Bio Inc.
  • Bio-Techne
  • Bruker Corporation
  • Thermo Fisher Scientific Inc.
  • Shimadzu Corporation
  • New England Biolabs.
  • Waters.co.
  • Merck KGaA
  • Palleon Pharmaceuticals
  • Asparia Glycomics
  • RayBiotech Life,Inc.
  • Z Biotech,LLC.
  • Chemily Glycoscience
  • Lectenz Bio
  • 2BScientific

Report Coverage

  • Market Forecast
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives

Customization & Pricing

Available upon Request

Key Segments Covered in Glycobiology Industry Research

Product:

  • Instruments
  • Enzymes
  • Consumables
  • Kits and Reagents

Enzyme:

  • Galactosidases
    • Fucosidases
    • Chitinases
    • Acetylgalactosaminidase
    • Heparinase
    • PNGase F
    • Others
  • GlcNAc Transferases
    • Acetylglucosaminyltransferase
    • Exostosin
    • Others
  • Fucosyltransferases
  • GalNAc Transferases
  • Galactosyl Transferases
  • Glucuronosyltransferases
  • Glucosyltransferases
  • Pentosyltransferases
  • Carbohydrate Kinases
  • Neuraminidases
  • Sialyltransferases
  • Others

Application:

  • Drug Discovery and Development
  • Diagnostic Applications
    • Oncology
    • Immunology
    • Others
  • Industrial Applications
  • Therapeutic Applications
    • Oncology
    • Immunology
    • Others
  • Others

End User:

  • Biopharmaceutical Companies
  • Research Laboratories
  • Hospitals
  • Diagnostic Centers
  • Contract Research Organizations
  • Biotechnology Industries
  • Academic Institutes
  • Others

Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East and Africa

- Companies Covered in This Report -

  • Glycodiag
  • Tracxn Technologies Limited
  • Agilent Tecnologies, Inc.
  • Takara Bio Inc.
  • Bio-Techne
  • Bruker Corporation
  • Thermo Fisher Scientific Inc.
  • Shimadzu Corporation
  • New England Biolabs.
  • Waters.co.
  • Merck KGaA
  • Palleon Pharmaceuticals
  • Asparia Glycomics
  • RayBiotech Life,Inc.
  • Z Biotech,LLC.
  • Chemily Glycoscience
  • Lectenz Bio
  • 2BScientific

- Frequently Asked Questions -

The global market is currently valued at around US$ 1.3 Billion in 2022.

The global market is expected to reach valuation of around US$ 1.5 Billion by the end of 2023.

The global market is set to reach a valuation of US$ 6.2 Billion by the end of 2033.

Sales of the market are set to witness growth at a CAGR of 15.5% between 2023 and 2033.

Demand for the global market increased at a 12.3% CAGR between 2015 and 2022.

The U.S., Japan, Germany, France, and Canada account for most demand within the market, currently holding around 62.8% market share.

The U.S. accounts for around 88.3% share of the North American market in 2022.

The China market held a share of about 4.5% in the global market in 2022.

The U.K. market held around 15.5% market share of the Europe market in 2022.

Glycodiag, Tracxn Technologies Limited, Agilent Technologies, Inc., Takara Bio Inc., Bio-Techne, Bruker Corporation, Thermo Fisher Scientific Inc., Shimadzu Corporation, New England Biolabs, Waters.co. Merck KGaA, Palleon Pharmaceuticals, Asparia Glycomics, RayBiotech Life,Inc., Z Biotech,LLC., Chemily Glycoscience, Lectenz Bio and 2BScientific are the key players active within the global market.

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