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Host Cell Contaminant Testing Market

Global Market Study on Host Cell Contaminant Testing: High Demand to be Witnessed from Academic and Research Institutions During 2017 - 2025

Host Cell Contaminant Testing Market Segmented By PCR-based Assays, ELISA-based Assays Product Type in Microbial, Mammalian Platform

Introduction

Host cell proteins essentially refers to the heterogeneous group of proteins that are derived from host cells such as yeast, E-coli, and mammal, among others. They differ largely form each other in terms of properties, isoelectric point, and molecular mass. Identification and quantification of host cell contaminants is very important in the development of biopharmaceuticals. A range of techniques are used for identification of host cell contaminants, for instance, immuno-specific techniques such as ELISA, Western Blot, PCR, and non-specific techniques such as electrophoresis and LC-MS.

In general, semi-quantitative or quantitative methods are used for sample purification. However, during the biopharmaceutical development, an ideal method is required to identify all kinds of host cell contaminants with high throughput, and quantitative analysis.Introduction

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Bio-pharmaceutical companies to lead among end users

Among all end users of host cell contaminant testing, the global market is expected to be led by bio-pharmaceutical companies. It accounted for a share of 51.4% of the global host cell contaminant testing market in 2017 and is expected to maintain a dominant position in the market over the course of the forecast period. Many pharmaceutical companies epitomize several prominent connections in the chain of pharmaceutical development, as they have the economic strength and drug manufacturing experience needed to introduce novel drugs into the market.

Additionally, they have production capabilities and necessary market infrastructure required for a product to reach the desired marketplace. Thus, several nascent biopharmaceutical companies depend on partnerships and agreements with large-scale pharmaceutical companies in order to finance, enhance their customer base, make expensive products, conduct clinical trials, and market their products.

Equally, almost all large-scale pharmaceutical companies are in incessant need for new, effective, and advanced therapeutic techniques and are also know that it is not possible to generate everything in-house. Thus, bio-pharmaceutical companies investing on host cell contaminant testing are entering into partnership deals.

As with investors, the companies are striving to manage and moderate risks, thus giving precedence to low-risk, and late-stage products such as antibodies and small molecule drugs. Meanwhile, the early stage host cell contaminant therapies only occupy a small amount of the deal values and deals. Many bio-pharmaceutical companies are yet to venture into the cell contaminant testing space.

global host cell contaminant testing market

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Contract research organizations to catch up with contract manufacturing organizations

Contract research organizations are likely to give a tough competition to contract manufacturing organization in the years to follow. New investments into a company tend to dilute the existing investors as now they have a comparatively small slice of a large pie. However, there are other ways to finance drug development without causing harm to the present group of investors. They can have a definitive agreement as a contract research organization or a contract manufacturing organization with leading companies for a certain tenure.

Contract research organizations and contract manufacturing organization identify the target disease, do a pre and post-clinical evaluation, conduct a toxicology and safety test, and clinical trial design and implementation. Same is with contract manufacturing organizations that manufacture certain specific drugs with specific requirements with their relevant equipment required for the specific type of drug manufacturing.

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Market Segmentation

Attribute Details

Region

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa

Product Type

  • PCR-based Assays
  • ELISA-based Assays
Platform
  • Microbial
  • Mammalian
  • Others
Application
  • Research & Development
  • Clinical Applications

End User

  • Biopharmaceutical Companies
  • Contract Research Organizations
  • Contract Manufacturing Organizations
  • Academic & Research Institutes
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- Companies Covered in This Report -

  • BioGenes GmbH
  • Bio-Rad Laboratories, Inc.
  • Cisbio Bioassays
  • Cygnus Technologies LLC (A Maravai Lifesciences Company)
  • Enzo Life Sciences, Inc.
  • ForteBio (A Pall Company)
  • GE Healthcare Life Sciences
  • Molecular Devices LLC
  • ProteinSimple (A BioTechne Brand)
  • Thermo Fisher Scientific, Inc.
  • Others

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