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Protein Purification Reagents Market

Market Study on Protein Purification Reagents: North America to Continue Leading Global Market

Protein Purification Market Segmented By Instruments, Consumables Type with Ultrafiltration, Precipitation, Chromatography, Electrophoresis, Western Blotting Technology

Protein Purification Reagents Market Outlook (2022-2032)

The global protein purification reagents market is projected to increase to a valuation of US$ 21 Bn by 2032, up from its present size of US$ 7.8 Bn, expanding at a noteworthy CAGR of 10.5% over the next ten years.

Based on technology, the chromatography vertical accounts for 25.1% share in the global market.

Report Attribute Details

Protein Purification Reagents Market Size (2022E)

US$ 7.8 Bn

Projected Market Value (2032F)

US$ 21 Bn

Global Market Growth Rate (2022-2032)

10.5% CAGR

Value Share of North America (2021A)


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Which Factors are Lending Impetus to the Market for Protein Purification Reagents?

“Increasing R&D Activities across Pharmaceutical & Biotechnology Industry”

In recent years, there has been a significant increase in R&D activities that are taking place in the pharmaceutical and biotechnology sectors. Along with this, funding provided by governments and related bodies for research activities is also creating growth avenues for protein purification reagents market players.

Technological advancements that are taking place in protein purification solutions are predicted to substantially contribute to market growth. Furthermore, the growing requirement for high-resolution information related to protein structure is also estimated to serve as one of the key factors driving expansion opportunities in the market.

“Introduction of Automated Workstations Propelling Market Growth Opportunities”

At present, there is a high requirement to identify novel ligands for the discovery of drugs. These newly developed drugs are helpful in ensuring effective solutions for targeted end users.

The introduction of automated workstations is likely to provide assistance to reduce manual efforts. Further, the growing requirement for rapid purification kits is also estimated to offer opportunities in the market.

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What are the Limiting Factors for the Protein Purification Reagents Market?

“High Cost of Protein Purification Solutions to Limit Expansion Opportunities”

Issues related to the high cost of protein purification solutions and time consumption are projected to restrict growth avenues in the market. In addition, a dearth of skilled and trained researchers is also expected to restrain the market over the coming years.


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North America Leads Global Market for Protein Purification Reagents

North America is anticipated to dominate the market owing to an increasing number of R&D activities in the pharmaceutical and biotechnology sectors. Further, technological advancements taking place in protein purification in the North American region are also predicted to contribute to market growth opportunities.

The Asia Pacific market is expected to grow at a significant rate over the coming, especially led by India and China. A larger patient pool in these developing nations has been projected, which will lead to high market growth. Furthermore, rising government funding for numerous R&D activities and an increasing count of research projects are likely to contribute to growth opportunities in the market.

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Recent Developments

  • GE Healthcare Life Sciences announced its acquisition of BK Medical in December 2021. BK Medical was in the possession of Altaris Capital Partners, LLC and a cash payment of US$ 1.45 Bn has been paid for this acquisition by GE Healthcare Life Sciences.

Protein Purification Reagents Market: Overview

Proteins are macromolecules, consisting of one or more long chains of amino acid residues linked by peptide bonds. Protein structure comprises primary, secondary, tertiary, and quaternary structure levels. Its function and shape depend upon the amino acid sequence and the sequence of bases in the genes.

Protein function in an optimal condition, and denatures when exposed to extreme conditions. Change in temperature, salt concentration, and pH can also denature the protein. Protein purification is the series of processes intended to isolate a single type of protein from a complex mixture.

Protein purification is done with the help of various processes such as crude extract, salting out, fractionation, and dialysis. In fractionation, protein is separated into different fractions based on the size of the charge, whereas in crude extract, protein is separated by breaking cells with the help of osmosis or homogenization.

Separation of protein is based on the chemical and physical properties such as size, shape, surface-exposed hydrophobic residues, solubility, isoelectric point, and charged surface residues. Protein purification is done for genetic engineering, antibody production, sequence determination, structural determination, finding inhibitors, and detailed kinetic studies. It is also used for the extraction of purified protein for enormously precious biochemical reagents. Protein purification is done with the help of techniques such as chromatography and electrophoresis.

Chromatography is a group of separation techniques, characterized by a distribution of the molecule to be separated between the stationary and mobile phases. Affinity chromatography, ion exchange chromatography, gel filtration chromatography, and high-pressure liquid chromatography are some of the types of chromatography techniques used in protein purification.

In addition, electrophoresis is the technique used to separate macromolecules based on size and it applies a negative charge as protein moves towards a positive charge. Gel electrophoresis and capillary electrophoresis are some of the electrophoresis techniques used in protein purification.

Key Market Players

Major companies operating in the global protein purification reagents market are Merck Millipore, Takara Bio Company, Applied Biosystems, Qiagen, Advanced Bioscience Laboratories, Inc., GE Healthcare Life Sciences, PerkinElmer, Inc., Thermo Fisher Scientific, Agilent Technologies, and Bio-Rad Laboratories, Inc.

Protein Purification Reagents Industry Report Scope



Forecast period


Historical data available for


Market analysis

USD Million for Value

Key regions covered

  • North America
  • Europe
  • Latin America
  • East Asia
  • The Middle East & Africa
  • South Asia & Pacific

Key countries covered

  • U.S.
  • Canada
  • UK
  • Germany
  • France
  • Spain
  • Turkey
  • Italy
  • Japan
  • China
  • India
  • South Korea
  • Brazil
  • Chile
  • Colombia
  • Colombia
  • South Africa
  • UAE

Key market segments covered

  • Product
  • Technology
  • Application
  • End Use
  • Region

Key companies profiled

  • Merck Millipore
  • Takara Bio Company
  • Applied Biosystems
  • Qiagen
  • Advanced Bioscience Laboratories, Inc.
  • GE Healthcare Life Sciences
  • PerkinElmer, Inc.
  • Thermo Fisher Scientific
  • Agilent Technologies
  • Bio-Rad Laboratories, Inc.

Report Coverage

  • Market Forecast
  • Company Share Analysis
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives

Customization & pricing

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Protein Purification Reagents Industry Research by Category

By Product Type:

  • Instruments
  • Consumables

By Technology:

  • Ultrafiltration
  • Precipitation
  • Chromatography
  • Electrophoresis
  • Western Blotting
  • Others

By Application:

  • Drug Screening
  • Biomarker Discovery
  • Protein-protein Interaction Studies

By End Use:

  • Academic and Research Institutes
  • Hospitals
  • Pharmaceutical and Biotechnological Companies
  • CROs

By Region:

  • North America
  • Europe
  • Latin America
  • East Asia
  • Middle East & Africa
  • South Asia & Pacific

- Companies Covered in This Report -

  • Merck Millipore
  • Takara Bio Company
  • Applied Biosystems
  • Qiagen
  • Advanced Bioscience Laboratories, Inc.
  • GE Healthcare Life Sciences
  • PerkinElmer, Inc.
  • Thermo Fisher Scientific
  • Agilent Technologies
  • Bio-Rad Laboratories, Inc.

- Frequently Asked Questions -

The global market for protein purification is currently valued US$ 7.8 Bn. 

North America accounts for the highest market share of over 45%.

Chromatography leads the protein purification reagents market with 25.1% market share.

The global protein purification reagents market is set to surge ahead at 10.5% CAGR. 

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