In Vitro Protein Expression Market

Global Market Study on In Vitro Protein Expression: Rabbit Reticulocytes System to Witness a Boost in Adoption Across Various Applications

In Vitro Protein Expression Market Segmented By coli System, Rabbit Reticulocytes System, Wheat Germ System, Insect Cells System, Mammalian System

  • January-2018
  • PMRREP21727
  • 210 Pages
  • Healthcare


The global in vitro protein expression market is anticipated to grow at a robust rate to reach a significant value by the end of the assessment period. The in vitro protein expression market has been experiencing noteworthy growth during 2012-2016 period. It is projected to grow at a value CAGR of 6.0% throughout the period of forecast to reflect a market value more than US$ 250 Mn by the end of 2025 from a market valuation of about US$ 157 Mn in 2017.

This growth can be attributed towards increasing demand for continuous-exchange in vitro protein synthesis, growing consumption of in vitro protein systems in bio pharma and biotech companies, increasing demand for simple and effective protein production methods and increasing technological advancements.

Strong research and development initiatives associated with in vitro protein synthesis have expanded the adoption of in vitro protein expression systems. These systems are witnessing increased use in protein library generation for customized drug development, functional genomic studies and expression of virus-like particles and in many other applications.

In addition, in vitro protein expressions are potential tools used in genetic diagnostics. They can also be used in conjunction with truncated proteins as a technique in order to detect mutations in the marker genes. Moreover, the in vitro protein expression is a flexible, rapidly growing and a potent technology used in several applications. Additionally, protein labelling and gene mutation is pushing the use of in vitro protein expression market.

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  • Thermo Fisher Scientific, Inc.
  • Takara Bio Company
  • New England Biolabs
  • Promega Corporation
  • Jena Bioscience GmbH
  • GeneCopoeia, Inc.
  • Biotechrabbit GmbH
  • Cube Biotech GmbH
  • CellFree Sciences Co., Ltd.
  • Bioneer Corporation
  • Others.

E.coli systems to reflect a major share in the global in vitro protein expression market

E.coli in vitro protein expression system is widely used protein expression system owing to its cost effectiveness and higher protein yield. The E.coli system segment is estimated to be the largest with a high market valuation during the period of forecast. The E.coli system segment in 2017 reflected a valuation of about US$ 74 Mn and is anticipated to touch a market valuation a little under US$ 120 Mn by the end of the year of assessment (2025). This segment is projected to expand at a remarkable CAGR of 6.1% throughout the period of assessment. Simple and inexpensive extract preparation offered by E.coli system makes it a highly lucrative product type segment.

Mammalian system segment in the product type category is expected to highly contribute to the growth of the global market. The segment reflected a value of about US$ 31 Mn in 2017 and is the second largest segment and is expected to grow at a high rate during the 2017-2025 forecast period.

The insect cells system and wheat germ system segments by product type are comparatively low in valuation and are poised to register a moderate CAGR during the forecast period. Of these, the wheat germ system segment is relatively bigger than the insect cells system segment.


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E.coli and mammalian systems’ scenario in North America

In North America, the US being a lucrative market in the region, the in vitro protein expression market is witnessing spurring adoption, E.coli and mammalian systems being at the forefront of growth. The mammalian system in this region is expected to witness higher demand in the coming years and the segment is projected to rise at a stellar CAGR during the forecast period. The E.coli system segment in North America is projected to register a CAGR of 5.8% during the forecast period.

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Market Taxonomy

Product Type
  • coli System
  • Rabbit Reticulocytes System
  • Wheat Germ System
  • Insect Cells System
  • Mammalian System

Expression Mode
  • Continuous Flow Expression
  • Batch Expression

End User
  • Biotechnological Companies
  • Pharmaceutical Companies
  • Contract Research Organizations
  • Academic and Research Institutes

  • Enzyme Engineering
  • Protein Labeling
  • Protein-Protein Interaction
  • Protein Purification

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • MEA

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