Global Market Study on Serum-Free Media: Chinese Hamster Ovary Cell Culture to Remain Dominant Media Type Through 2026


Serum Free Media  Market
  • Published On : Sep-2018 |
  • Pages : 188 Pages |
  • Format : Serum Free Media  Market Serum Free Media  Market Serum Free Media  Market Serum Free Media  Market

Market Value and Forecast

The global Serum-Free Media market is expected to expand at a CAGR of 7.3% over the forecast period 2018–2026. By media type the global Serum-Free Media market is expected to be dominated by CHO cell culture media with 19.6% market share in 2018 followed by protein expression media.

Market Dynamics

The global serum-free media market is segmented on the basis of media type, end user and region. The global serum-free media market is segmented on the basis of media type as protein expression media, stem cell media, hybridoma media, primary cell media, insect cell media, immunology media, Chinese hamster cell (CHO) culture media and chemically defined media.

The serum-free media market is driven by the increasing production of biopharmaceuticals due to increasing number of biologics used for treatment of different disease. Serum-free media offers superior cell culture growth as compared to serum containing media. Serum contains unidentified components which may hamper the final output qualitatively or quantitatively and to prevent that various biopharmaceutical companies are preferring serum-free media for the cell culture. Downstream process is regarded as the bottle neck of biopharmaceutical production and serum-free media helps to minimize the complexity of downstream process which further enhances adoption of serum-free media for biopharmaceutical production.

By media type serum-free media market is dominated by CHO cell culture media due to higher adoption by biopharmaceutical companies for the cell culture growth. CHO cells are most widely used for industrial production of recombinant therapeutics in the mammalian hosts hence dominating the serum-free media by market values share. Chinese hamster ovary cell culture is widely used for the commercial production of therapeutic proteins.

Protein expression serum-free media is second most lucrative segment by media type due to it’s higher adoption for the recombinant protein production which allows analysis of gene regulation, protein structure and function analysis. Stem cell media is the fastest growing segment in the serum-free media market due to rapidly increasing usage of stem-cells in different therapies. Stem cell media in serum-free media market is expected to expand with the CAGR of 7.9% over the forecast period attributing to vast research going on around use of stem cells.

Increasing production of antibodies for therapeutic use expected to enhance use of hybridoma media further enhancing serum-free media market growth. As the monoclonal antibodies can be used for the prevention, diagnosis and treatment of different diseases hybridoma media serves as the effective way for their commercial production enhancing serum-free media market growth.

Primary cells have finite lifespan in cell culture and hence after certain period of time they die. To use primary cell in serum-free media for cell culture growth it requires addition of cytokines and growth factors to optimum level. Whereas primary cell culture often remains physiologically and therapeutically unaltered which enhances adoption of primary cell culture in serum-free media market.

Insect cell media in serum-free media market is another media type which is used for the production of viral pesticides, recombinant proteins and vaccines. Insect cell media in serum-free media have over 100 species which offers diverse and effective mean for cell culture growth.

Immunology media in serum-free media is used to culture immune cells which play important role in immune therapy in managing diseases such as cancer and infectious disease. Immune cell culture media is third most lucrative and one of the fastest growing segment by media type in the serum-free media market.

Chemically defined media in serum-free media is least lucrative segment by media type. Exclusion of serum from cell culture reduces the quantity of unknown components near to null and hence chemically defined serum-free media is least preferred.

Key Insights

  • The CHO cell culture media in serum-free media market is expected to represent a highest absolute opportunity of US$ 22.3 Mn in 2018 over 2019
  • Increasing adoption of serum-free media for the cell culture growth is attributed to it’s superior batch-to-batch consistency
  • Increasing number of contract manufacturing organizations (CMO) further expected to enhance serum-free media market
  • The urge for defined cell culture medium to analyse the role of each component further contributes significantly to the serum-free media adoption for cell growth
  • Biopharmaceutical companies are making extended efforts to enhance availability serum-free media by establishing their own manufacturing unit or acquiring CMOs for supply of cell culture media
  • The increasing research around the stem cells for different therapeutic usage and increasing academic research further expected to enhance stem cell serum-free media market
  • With increasing expenditure on R&D by the biopharmaceutical companies for the development of new biological products can enhance the serum-free media market revenue generation. In 2016, biopharmaceutical companies located in the United States invested more than US$ 90.0 billion in R&D with most of investment in the United States only

This Persistence Market Research (PMR) report examines the “Global Serum-free media Market’ for the period 2018–2026”. The primary objective of the report is to offer updates and information related to market opportunities in the global serum-free media market.

The Global Serum-free media Market is Segmented Based on:

  • Media Type
  • End User
  • Region

This report covers the global serum-free media market performance in terms of revenue contribution from various segments. The report begins with an overview and market definitions. The market viewpoint section underlines the macro-economic factors influencing the growth of the global serum-free media market along with detailing the opportunity analysis of the market. This is then followed by the key drivers, restraints and trends of the global serum-free media market.

By media type, the global serum-free media market is segmented into protein expression media, stem cell media, hybridoma media, primary cell media, insect cell media, immunology media, Chinese hamster cell (CHO) culture media and chemically defined media. The CHO cell culture media is expected to be the dominant segment in the global serum-free media market due to wide use in therapeutic protein production. The CHO cell culture media in serum-free media is high in North America and Europe due to high number of biopharmaceutical companies in the region. Whereas, chemically defined media in serum-free media remains least lucrative segment.

By end users, the global serum-free media market is segmented into biopharmaceutical companies, clinical research organizations and academic research centers.

By region, the global serum-free media market has been segmented into North America (the U.S. & Canada), Latin America (Brazil, Mexico, and Rest of Latin America), Europe (Germany, France, the U.K., Italy, Spain, Russia and Rest of Europe), Asia Pacific (China, India, Japan, Australia & New Zealand and Rest of Asia Pacific), and Middle East and Africa (GCC Countries, South Africa, Israel and Rest of MEA).

A detailed analysis has been provided for each region in terms of serum-free media market size, Y-o-Y growth rate, absolute $ opportunity, and attractive index. The forecast of the serum-free media market by country, media type and end user is represented in a tabular form. This section will help to understand the present scenario and opportunity of the serum-free media market in major countries by each segment.

In the next section of the report, the “Competitive Landscape” is included to provide report audiences with a dashboard view of the key competitor firms in order to access the key differentiators among the competitor firms. This section is primarily designed to provide clients with an objective and detailed comparative assessment of product offerings and strategies of key providers specific to a segment. The detailed profiles of players operating in the serum-free media market are also provided in the report, which highlight company description, product/segment overview, SWOT analysis, financial information, key developments related to the serum-free media market and the strategic overview.

The next section of the report highlights the serum-free media market outlook for 2018–2026 and sets the forecast within the context of the serum-free media market by region.

The above sections – by media type and end user – evaluate the historic market analysis and growth prospects of the serum-free media market for the period 2018–2026. We have considered 2017 as the base year and provided data for the forecast period.

The final section of the report represents the global scenario of the serum-free media market along with y-o-y growth and market forecast till 2026. This section also evaluates the global serum-free media market opportunity over the forecast period as well as the absolute dollar opportunity for each year. This section will help to understand the overall market growth for serum-free media and the opportunity analysis for every year over the forecast period.

To arrive at the serum-free media market size, bottom-up approach is used to validate the total market size obtained for the serum-free media market. The forecast presented in the report provides total revenue of the serum-free media market over 2018–2026. PMR uses the triangulation methodology, which is primarily based on experimental techniques such as patient-level data to obtain precise market estimations for the serum-free media market and insights on specific country/regions. The country-specific data is again analyzed to derive data at a regional level and then at a global level. This methodology ensures high quality and accuracy of information.

The factors considered while developing the estimates of the serum-free media market are epidemiology, treatment seeking rate, ratio of population prescribed with different serum-free media.

On the other hand PMR has also analyzed the serum-free media market by considering the revenue from the key players operating in the market. The key players are segmented at a Tier-level with respect to their revenues, product portfolio and geographical presence. This process involves analysis of annual reports of various companies, investor presentations, SEC filings, 10k reports, earning call transcripts and press releases. This task is done to fetch substantial information about the key players, their respective revenues and estimate their respective market share.

The revenue growth of the key players in serum-free media market is analyzed over the historical period and qualitative assessment of new product launches and innovations has been made in order to validate and align the resultant serum-free media market numbers. The market structure is closely studied and analyzed at a regional level to map and ascertain incremental $ opportunity for companies, for instance, supply from domestic/regional players, small-scale enterprises or unorganized segments is also taken into consideration to arrive at the final market numbers.

While forecasting the market size for the serum-free media market, we have considered the impact of several factors such as per capital healthcare expenditure, disposable income, new serum-free media products and approvals for new advanced serum-free media products, penetration of serum-free media products to various end users across all regions, among others. However, quantifying the serum-free media market across the aforementioned segments and regions is more a matter of quantifying expectations and identifying opportunities rather than rationalizing them after the forecast has been completed. In addition, we have taken into consideration the year-on-year growth to understand the predictability of the serum-free media market and to identify the right growth opportunities in the global serum-free media market.

Companies covered in Serum Free Media Market Report

Company Profiles

  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • GE Healthcare
  • Lonza
  • Corning Incorporated
  • Irvine Scientific
  • STEMCELL Technologies Inc.
  • PAN Biotech
  • MP Biomedicals, LLC
  • PromoCell GmbH
  • Others.
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