About the Report
Peptones are protein hydrolysates most preferably used in cell culture as a growth supplement. Protein supplements play an important role in cell culture media optimization, in both, mammalian and microbial cell culture processes. Peptones have been successfully used to improve the production of biosimilars, vaccines, and monoclonal antibodies. Growing burden of several lifestyle and chronic diseases is creating huge demand for new biologics. Peptones play an important role in the optimization of cell culture processes, hence, accelerate biologics production to meet global demand. Leading manufacturers such as Thermo Fisher Scientific, Inc., Merck KGaA, HI Media Laboratories, and Becton, Dickinson and Company are focusing on the global distribution of their products through acquisition, collaboration, and partnership activities. Emergence of e-Commerce has also increased the accessibility of peptone products from key manufacturers.
In its new study, Persistence Market Research offers insights about key factors driving the demand for peptone. The study points toward peptone from animal source being the most sought-after. Biopharmaceutical companies hold more than half of the market share, globally. The report also tracks global sales of peptone in over 20 high-growth markets, along with analysis of the impact of COVID-19 on the life science industry in general, and peptone in particular.
The COVID-19 pandemic had an impact on the peptone market in 2020 due to low availability of manpower, shut downs, and shifted focus toward COVID-19 research by biopharmaceutical companies. However, demand for these supplements increased in the latter stage of the pandemic. The supply chain crisis during lockdowns led to a halt in sales; however, sales resumed without adversely impacting the market in a big way.
Find Out More about the Report Coverage
- HiMedia Laboratories
- Merck KGaA
- Thermo Fisher Scientific Inc.
- Hardy Diagnostics,
- Solabia Group
- Global Bioingredients,
- Kerry Inc
- Nu-Tek BioScience, LLC.
What is the demand scenario for peptone in the future?
Process and media optimization play an important role in the large-scale manufacturing of potent biopharmaceuticals. Unlike microbial cell culture, mammalian cells have been found to be difficult for high yield and process optimization. Use and demand for protein supplements such as peptones have been exponentially rising in the last few years. Moreover, increasing focus on academic cell culture research and industrial research has created a gateway for manufacturers in the peptone supplements market. Peptones have advantages such as cost-effectiveness in the manufacturing and bulk production of biopharmaceuticals and antibodies. Peptone, as a supplement for cell culture, has revolutionized the biopharmaceutical manufacturing industry in developing therapeutics and novel biologics.
Rapid growth of biotechnology research is expected to boost demand for peptone during the forecast period of 2020 to 2030. Demand for biologics and growing preference for animal-free peptones are anticipated to transform the future of the biopharmaceutical industry.
All these factors are expected to create opportunities for the expansion of the peptone market size over the forecast period, projected to expand at a CAGR of over 4% through 2030.
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What is the impact of market consolidation on peptone demand?
Leading players in the peptone market are employing synergistic approaches for the distribution and manufacturing of products through various market consolidation activities. These synergies between companies are expected to help secure the future growth of partner companies and maintain their market share. Besides, key acquisitions will bolster research growth and development of new technologies to be implemented in bioprocess services.
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How is rising burden of life-threatening diseases aiding market growth?
Increasing life-threatening viral and chronic diseases all over the world have led to a surge in demand for novel therapeutics in order to prevent and cure the affected population. Biopharmaceutical products are preventative medicines or therapeutics that are derived from the metabolites naturally present in living organisms.
Peptones are used as a protein supplement in cell culture and fermentation processes in order to produce novel biopharmaceutical products. Further, growing chronic disease population and increasing demand for novel therapeutics are factors expected to propel demand for peptone over the coming years.
- For instance, according to WHO in 2002, burden of chronic disease was around 43% of all diseases globally, and their contribution to death was 60%. However, by 2020, it was estimated that, death rate due to chronic disease will rise to 73%, and the burden will be around 60%.
Moreover, increasing economic prosperity and health consciousness would also fuel global demand for peptone.
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What is the impact of investments in manufacturing facility expansion on the peptone market?
Majority of companies are looking forward to expanding their production capacity through expansion of manufacturing facilities. Considerable investments in the expansion of biopharmaceutical products such as peptone manufacturing is one of the major trends among key players in the market.
In order to produce high-quality culture media and substances to meet global demand, leading players are increasingly focusing on ramping up their capacity to produce ready prepared cell culture products.
- For instance, in October 2020, Nu-Tek BioScience got approval for the development of a manufacturing facility in North America, in order to fortify its animal-free peptone production capacity.
Increasing investments in manufacturing capacity expansion are expected to favor the growth of the peptone market over the forecast period.
How do academic and pharmaceutical research collaborations impact the peptone landscape?
Various pharmaceutical and biopharmaceutical companies are focusing on a research-based collaborative approach for the development of their products for various industrial applications. To increase the quality, affordability, and sustainability of their products used in cell culture, microbiology, and molecular biology, several market leaders are strategically looking for collaboration with various academic research institutes.
Academic research institutes have been involved in cost-effective basic research activities to develop novel therapeutics. On the other side, industrial organizations and governments also prefer low-cost ways to continue research & development programs. A majority of basic research in biotechnology has been carried out at academic institutes, to bring products to the market with the aim of generating profits.
- For example, Hi-Media Laboratories collaborated with various premier academic institutes in India to explore several industrial biotechnology projects in collaboration with Biotechnology Industry Research Assistance Council (BIRAC).
Will he rising biopharmaceutical industry in China lead to significant demand for peptone?
China is well known for its large scale exports of Active Pharmaceutical Ingredients (APIs) and generic drugs. The biopharmaceutical industry in China is growing rapidly, and has been making significant progress in the last few years. As per CFDA, more than 1,653 grants have been approved for biologics manufacturing in the country; among them, more than 95% are therapeutic biologics to be launched in the Chinese market. Moreover, in 2018, there were 401 antibodies in the pipeline. Rising healthcare expenditure and increasing novel therapeutics launches by international and domestic drug manufacturers in China have laid a solid foundation for the growth of the biopharmaceutical industry in this country.
Peptones are used as a major ingredient in cell culture and biopharmaceutical manufacturing. Therefore, increasing manufacturing of biologics in China is expected to surge demand for peptone in future. Advancement of microbial and mammalian cell culture process optimization techniques for large-scale biologics production over time is also anticipated to lead to high adoption of peptone. China is one of the known leaders for large-scale biologics production and adoption of technologies. Further, presence of a high number of domestic and international pharma companies in the country is also expected to boost market growth over the coming years.
How is increasing spending on biopharmaceutical R&D surge the growth of peptone in the U.S.?
Research & development activities are the backbone of the biopharmaceutical industry. Increasing spending on pharmaceutical R&D will bolster growth of the market in a particular region. The U.S. contributed to the highest market share in the biopharmaceutical industry through high spending on pharmaceutical R&D, over the years. The U.S. continues to lead the biopharma market, it raised funds of around US$ 92.7 billion in 2019.
Protein supplements are most important for biopharmaceutical R&D and production of novel therapeutics. Robust investments in novel biologics production by key countries such as the U.S. will provide high growth for the peptone market in the country. Rise of the biopharmaceutical industry and increasing spending by the U.S are expected to create lucrative growth opportunities for peptone manufacturers in the U.S.
How are the Indian R&D policies bolstering demand for peptone in the country?
The Government of India, in recent years, has implemented several favourable policies to encourage biopharmaceutical companies for novel drug and molecule discovery. The government has taken various initiatives, such as the formation of BIRAC (Biotechnology Industry Research Assistance Council), to help and support biotech R&D through collaboration and funding between academia and industry. The government is also involved in the establishment of biotech/pharma parks across different parts of the country in collaboration with state governments, as part of the ‘Make in India’ initiative. Further, CDSCO (Central Drugs Standard Control Organization), in 2019, amended the ‘clinical trial rules’, which favour domestic and international pharma companies for clinical trials and accelerates drug approval processes.
- According to Invest India, India is the third-largest seller of medicines in the world. The country has over 3,000 pharma companies and a network of over 10,500 manufacturing facilities.
Clinical trial and research is now a major business in India, owing to factors such as numerous government-funded medical and pharmaceutical institutions with state-of-the-art facilities, which can serve as ideal centres for multi-centred clinical trials. R&D costs in India are substantially lower as compared to developed countries, and it is possible to conduct both, new drug discovery research and novel drug delivery system programs at competitive rates. All these factors are anticipated to surge demand for peptone in the country over the years to come.
How the presence of key market players benefitting the European Union?
Europe is the largest hub for biotechnology research, having world-class research institutes, hospitals, and medical research centres. Europe is home to 16 of the world's top life science universities out of the top 50. There are hundreds of biopharmaceutical companies based across Germany, France, and the U.K. Presence of prominent players such as Merck KGaA, Thermo Fisher Scientific Inc., and Becton, Dickinson and Company in Europe is expected to create remarkable returns for the region in the peptone space. Among the European countries, Germany is expected to be the leader in peptone, and is anticipated to witness significant growth over the forecast period. Moreover, biopharmaceutical research & development activities and growing contract research manufacturing in the U.K. will also create high demand for peptone within the country, and the region.
Which source is more preferred for peptones?
Peptones derived from animal sources will continue accounting for more than half of the global share among other source segments through the forecast period. According to Persistence Market Research, the segment of peptone derived from plant sources is expected to hold more than 30% of the market, in terms of revenue, in the year 2020. Availability of diverse products, low cost, and high adoption of peptones derived from animal sources for microbial cell culture are the leading factors behind the dominance of this segment.
However, peptones derived from plant sources reduce the risk of cell culture contamination. These types of peptones are mostly considered for mammalian cell culture, and are gradually increasing in popularity for a various research applications. As such, plant peptones are expected to progress at a high CAGR of around 5% over the forecast years.
How is increasing use of peptone in microbial cell culture impacting the Industry?
Peptones are widely being used for growth optimization of microbial cell culture in the biopharmaceutical industry. Increasing academic research activities coupled with large-scale microbial fermentation by pharmaceutical companies will increase the market share of microbial cell culture to more than 60% by application in the global market.
The peptone market is highly consolidated in nature with more than 10 key players operating across the world. The market is dominated by prominent manufacturers - Merck KGaA, Thermo Fisher Scientific Inc., Becton, Dickinson and Company, Hi-Media Laboratories, Eppendorf AG, and Danaher Corporation. Majority of these manufacturers are focused on offering a wide range of peptones for multiple applications such as microbial cell culture, mammalian cell culture, and bioprocessing. They are also focusing on acquisition and collaboration activities to improve their product quality and expand their product portfolios for use in various clinical and research fields.
- For instance, in December 2019, Sartorius acquired a majority stake of Biological Industries, which is an Israel-based cell culture media company.
- In February 2020, Neogen Corporation acquired Abtek Biologicals Ltd. — a U.K.-based developer and supplier of culture media supplements.
- In 2018, October, Thermo Fisher Scientific Inc. acquired the advanced bioprocessing business of BD (Becton, Dickinson and Company), a leading global medical technology company.
Some of the leading companies operating in the market are:
Thermo Fisher Scientific Inc.
Sartorius Stedim Biotech
Merck Millipore (Merck Group)
Celltainer Biotech B.V.
Parker Hannifin Corp
Mettler-Toledo International, Inc.
PreSens Precision Sensing GmbH
Rim Bio, Inc.
*The list is not exhaustive, and only for representational purposes. Full competitive intelligence available in the report.
Scope of Report
Historical Data Available for
USD Million for Value and Units for Volume
Key Regions Covered
Key Countries Covered
Key Segments Covered
Key Companies Profiled
Customization & Pricing
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Peptone Market by Category
- Soy Peptone
- Vegetable Peptone
- Beef Extract
- Casein Peptone
- Gelatin Peptone
- Brain Heart Infusion (Bovine)
- Brain Heart Infusion (Porcine)
- Casein (Acid Hydrolysate)
- Heart Infusion (Bovine)
- Heart Infusion (Porcine)
- Meat Peptone (Bovine)
- Meat Peptone (Porcine)
- Peptonized Milk
- Pork Heart Digest
- Protease Peptone
- Protein Hydrolysates
- Microbial Cell Culture
- Mammalian Cell Culture
- Plant Tissue Culture
- Yeast Culture
- Academic & Research Institutes
- Biopharmaceutical Companies
- Contract Research Laboratories
- North America
- Latin America
- South Asia
- East Asia
Key Questions Answered in Report
Q1. Which is the most lucrative market for peptones?
The U.S. currently leads the global market for peptone. Sales in the U.S. will be around 26% of total global share over the forecast period. Being a leader in biopharmaceutical manufacturing investments, the U.S. is expected to experience significant demand for peptone supplements over the entire forecast period.
Q2. Which product holds a significant share in the market?
Protein hydrolysates hold the highest (over three-fourth) market share in the global peptone landscape. Protein hydrolysates continue to expand, advance with time, and are gaining adoption all across the world.
Q3. In which application is the adoption of peptones high?
By application, adoption of peptones is higher in microbial cell culture, which accounts for around 64% of the market share in 2020. Increasing academic research institutes and rise in government funding for R&D activities will aid demand growth for peptone in microbial cell culture over the coming years.
Q4. Which are the leading companies offering peptone?
Some of the prominent companies offering peptone are Thermo Fisher Scientific Inc., Merck KGaA, BD., HiMedia Laboratories, Solabia Group, Biotecnica, and others.
Q5. Which are the challenges associated with peptone?
Peptones derived from animal, yeast, or plant sources are used for the growth of different cell types. However, due to the quality and lack of ultrafiltration of peptone products, there is always a chance for virus contamination in cell culture. Moreover, mostly, animal-derived peptones possess the risk of virus contamination during cell culture, which is the main challenge expected to restrain global market expansion.
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