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Submucosal Lifting Agent Market

Market Study on Submucosal Lifting Agent: PMR Foresees Various Opportunities, Analysing a Surge in Endoscopic Surgery, a Growing Prevalence of Gastrointestinal Disorders, and a Preference for Minimally Invasive Procedures

A Detailed Analysis of the Submucosal Lifting Agent Market Based on Increased Endoscopic Procedures and a Rising Demand for Minimally Invasive Techniques in Gastrointestinal Interventions

Submucosal Lifting Agent Market

The global submucosal lifting agent market is forecast to expand at a CAGR of 7.0% and thereby increase from a value of US$ 1.1 Bn in 2023 to US$ 1.8 Bn by the end of 2030.


Key Insights

Submucosal Lifting Agent Market Size (2023E)

US$1.1 Bn

Projected Market Value (2030F)

US$1.8 Bn

Global Market Growth Rate (CAGR 2023 to 2030)


Historical Market Growth Rate (CAGR 2018 to 2022)


Revenue Share of Top Four Countries (2022E)


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Market Introduction and Definition

A submucosal lifting agent is a medical substance used in endoscopic procedures, primarily during endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). The primary aim of submucosal lifting agents is to create a separation between the mucosal and submucosal layers of the gastrointestinal tract, facilitating the visualization and dissection of lesions or tumors. This lifting effect aids in the safe and efficient removal of abnormal tissues, contributing to improved diagnostic and therapeutic outcomes in gastrointestinal endoscopy. Submucosal lifting agents play a crucial role in minimizing the risk of perforation and enhancing the precision of endoscopic interventions, making them essential tools in the field of gastroenterology.

The increasing prevalence of gastrointestinal diseases including colorectal cancer, necessitating advanced endoscopic procedures for diagnosis and treatment. The rising adoption of minimally invasive techniques in gastrointestinal interventions further propels the market, with submucosal lifting agents being integral to enhancing the safety and efficacy of these procedures. Opportunities abound for market players to innovate and develop novel lifting agents with improved lifting capabilities and reduced adverse effects. Additionally, the growing awareness among healthcare professionals about the benefits of submucosal lifting agents is likely to contribute to market expansion, as these agents continue to be indispensable in the evolving landscape of gastrointestinal endoscopy.

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Market Dynamics

Increasing Prevalence of Gastrointestinal Diseases

The Submucosal Lifting Agent Market is witnessing substantial growth driven by the increasing prevalence of gastrointestinal diseases, particularly those requiring endoscopic interventions. Conditions such as colorectal neoplasms and early-stage gastrointestinal cancers often necessitate precise and minimally invasive procedures. Submucosal lifting agents play a pivotal role in these endoscopic interventions by creating a submucosal cushion, allowing for better visualization and safer removal of lesions. The rising incidence of gastrointestinal diseases, coupled with a growing emphasis on early detection and intervention, propels the demand for submucosal lifting agents, contributing to the overall market growth.

In addition, Advancements in endoscopic techniques are serving as another key driver propelling higher market growth in the Submucosal Lifting Agent Market. As endoscopy continues to evolve, there is a heightened focus on enhancing the precision and safety of procedures. Submucosal lifting agents are integral to advanced endoscopic techniques, providing a controlled and efficient lift of the mucosal layer during interventions. Innovations in both endoscope design and the formulation of submucosal lifting agents contribute to improved procedural outcomes and patient safety. The continuous refinement of endoscopic techniques, often involving the use of submucosal lifting agents, attracts healthcare providers and endoscopists, fostering a greater adoption of these agents in various gastrointestinal procedures and consequently driving market growth.

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Market Restraints

Regulatory Compliance and Impact on Dominance

One factor that might significantly affect the market performance of the Submucosal Lifting Agent Market is the stringent landscape of regulatory compliance, influencing the dominance of specific products and companies. The development, approval, and commercialization of submucosal lifting agents require adherence to rigorous regulatory standards set by health authorities. Companies capable of efficiently navigating these regulatory pathways establish dominance by bringing products to market in a timely manner. Regulatory compliance not only ensures the safety and efficacy of submucosal lifting agents but also determines the competitive landscape. Companies adept at meeting and surpassing regulatory requirements gain a strategic advantage, influencing their dominance and overall market performance within the Submucosal Lifting Agent Market.

Technical and Procedural Challenges

The Submucosal Lifting Agent Market faces challenges associated with technical and procedural complexities during endoscopic interventions. Achieving an optimal submucosal lift, crucial for accurate lesion visualization and safe removal, requires a delicate balance. Technical challenges arise in ensuring uniform and controlled elevation without causing damage to the mucosal layer. Moreover, variations in endoscopic techniques and procedural nuances among healthcare providers contribute to challenges in standardization. Overcoming these technical and procedural hurdles is vital for the widespread adoption of submucosal lifting agents and their seamless integration into diverse endoscopic procedures, impacting the overall growth and acceptance within the market.

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Advancements in Formulation Techniques to Propose Great Promise

One key opportunity for revenue growth in the Submucosal Lifting Agent Market lies in advancements in formulation techniques. Innovations in creating lifting agents with improved viscosity, prolonged lifting duration, and reduced adverse effects can significantly enhance the market's attractiveness. Market players can invest in research and development to formulate agents that offer superior lifting capabilities while maintaining safety profiles. Tailoring the formulations to address specific challenges, such as prolonged lifting in complex procedures can open new avenues for market expansion and increased revenue.

Moreover, collaborating with endoscopy equipment manufacturers presents another lucrative opportunity for revenue augmentation in the Submucosal Lifting Agent Market. Partnering with manufacturers can lead to the development of integrated solutions that combine advanced lifting agents with cutting-edge endoscopic technologies. Such collaborations can offer comprehensive packages to healthcare providers, streamlining the adoption of both lifting agents and compatible endoscopy equipment. This synergistic approach not only enhances the market presence of lifting agents but also fosters a holistic ecosystem that addresses the evolving needs of gastrointestinal endoscopy, driving revenue growth through bundled offerings.

Analyst Viewpoint

The submucosal lifting agent market presents a dynamic landscape marked by the escalating demand for minimally invasive endoscopic procedures. With the increasing incidence of gastrointestinal disorders and the imperative need for precise interventions, submucosal lifting agents have become integral tools in the hands of healthcare professionals. The market is witnessing a paradigm shift with a surge in applications, particularly in polyp removal and early-stage cancer management, indicating a pivotal role in advancing gastroenterological care. Furthermore, the swift adoption is propelled by Europe, emerging as a frontrunner due to its robust healthcare infrastructure. As technology continues to evolve, the market is poised for innovation, with ingredients like Hyaluronic Acid and applications in early-stage cancers driving the forefront of development. The analyst perspective underscores a promising future, where the Submucosal Lifting Agent Market is not merely meeting current needs but shaping the future landscape of gastrointestinal healthcare.

Supply-side Dynamics

The supply-side dynamics in the Submucosal Lifting Agent Market are shaped by a combination of factors, including research and development, manufacturing capabilities, and regulatory compliance. Research and development efforts play a pivotal role as companies strive to formulate advanced submucosal lifting agents with improved efficacy and safety profiles. Innovations in the composition of these agents contribute to enhanced lift performance and reduced procedural risks during endoscopic interventions. Manufacturing capabilities are equally crucial to meet the growing demand for these agents efficiently. Companies investing in state-of-the-art manufacturing processes ensure the production of high-quality, standardized submucosal lifting agents. Furthermore, regulatory compliance is paramount, with stringent requirements influencing product approval and market entry.

China assumes a significant role as a major supplier in the Submucosal Lifting Agent Market, contributing to the global availability of these critical medical products. Chinese companies are actively engaged in the manufacturing and supply of submucosal lifting agents, leveraging the country's robust manufacturing capabilities and cost-effective production processes. China's role extends beyond catering to domestic demand, as these companies export their products globally, influencing the overall dynamics of the market. The country's prominence as a major supplier enhances the diversity of available products, fosters competition, and contributes to the continuous advancement of submucosal lifting agent technologies on a global scale.

Market Segmentation

Which Ingredient are Expected to Benefit the Most from Revenue Generation?

Extensive Sales for Ingredient Due to Safety Profile and Versatility

The dominant category in the Submucosal Lifting Agent Market is Sodium Hyaluronate, recognized for its optimal lifting properties and compatibility with endoscopic procedures. As a naturally occurring polysaccharide, Sodium Hyaluronate exhibits excellent viscoelasticity, contributing to an effective separation between mucosal and submucosal layers during endoscopic interventions. Its biocompatibility and ability to maintain lifting duration make it a preferred ingredient in submucosal lifting agents. Furthermore, the fastest-growing category in the Submucosal Lifting Agent Market is Poloxamers, owing to their ability to enhance viscosity and stability in lifting agent formulations. Poloxamers, such as Poloxamer 188, play a pivotal role in improving the overall performance of lifting agents by providing a controlled and prolonged lifting effect.

What Type Will Be Targeted the Most for Installations?

Highest Percent Share Attributed to Hyaluronic Acid Owing to Rising Requirements for Real-time Data Monitoring

The dominant category in the Submucosal Lifting Agent Market is Hyaluronic Acid, recognized for its unparalleled biocompatibility and efficient lifting properties. As a naturally occurring substance in the human body, Hyaluronic Acid is well-tolerated and exhibits a high degree of safety in endoscopic procedures. Its ability to create a stable and prolonged lifting effect between mucosal and submucosal layers makes it a preferred choice for healthcare professionals. Furthermore, The fastest-growing category in the Submucosal Lifting Agent Market is Eleview, owing to its exceptional attributes that enhance visibility and overall procedural performance.

Which Area of Applications to be Focused on the Most Regarding Sales?

Polyps Applications to Widen Footprint Due to Primary Recipients of Submucosal Lifting Agents

The dominant category in the Submucosal Lifting Agent Market application is Polyps, with these abnormal growths being the primary recipients of lifting agents during endoscopic procedures. Polyps, commonly found in the gastrointestinal tract, necessitate precise and safe removal to prevent potential malignancies. Submucosal lifting agents play a crucial role in facilitating the elevation and separation of mucosal layers, allowing healthcare professionals to accurately identify and excise polyps. Furthermore, the fastest-growing category in the Submucosal Lifting Agent Market application is Early-stage Cancers. The swift growth is fueled by the increasing adoption of submucosal lifting agents in the management of early-stage cancers within the gastrointestinal tract.

Why are Hospitals to be Dominant Regarding Sales?

Hospitals to Dominate Sales Owing to Epicenters of Comprehensive Endoscopic Interventions

The dominant category in the Submucosal Lifting Agent Market's end-user segment is Hospitals, serving as the epicenters for comprehensive endoscopic interventions. Hospitals play a pivotal role in gastrointestinal healthcare, housing specialized departments and equipped facilities for advanced endoscopic procedures. Furthermore, the fastest-growing category in the Submucosal Lifting Agent Market's end-user segment is Specialty Clinics, emerging as niche providers of specialized endoscopic care. Specialty clinics, often focused on gastroenterology or endoscopy, are experiencing rapid growth due to their ability to offer targeted and personalized interventions.

Top Regional Markets

Strategic Healthcare Infrastructure and Rising Endoscopic Procedures to Fuel Growth for Easier Market Adoption

Europe emerges as a dominating region in the Submucosal Lifting Agent Market due to its strategic healthcare infrastructure and the increasing prevalence of endoscopic procedures. The region boasts well-established healthcare systems, fostering the adoption of advanced medical technologies, including submucosal lifting agents. With a focus on preventive healthcare and early intervention, European countries witness a surge in gastrointestinal endoscopic procedures that necessitate the use of lifting agents. The presence of leading medical research centers and a proactive approach to medical innovation further solidify Europe's dominance, making it a pivotal player in driving advancements and widespread acceptance of submucosal lifting agents in the realm of gastrointestinal healthcare.

Growing Burden of Gastrointestinal Diseases and Increased Healthcare Accessibility to Advance Growth

South Asia & Pacific emerges as the fastest-growing region in the Submucosal Lifting Agent Market, fueled by a dual surge in the burden of gastrointestinal diseases and improved healthcare accessibility. The region witnesses a notable increase in gastrointestinal conditions, emphasizing the need for advanced endoscopic interventions, including the use of submucosal lifting agents. Concurrently, efforts to enhance healthcare infrastructure and accessibility in South Asia & Pacific facilitate the adoption of cutting-edge medical technologies. The combination of a rising disease burden and heightened healthcare investments creates a conducive environment for the accelerated growth of the Submucosal Lifting Agent Market in South Asia & Pacific, positioning it as the fastest region in the market.

Competitive Intelligence and Business Strategy

Prominent organizations, including Laborie, STERIS, Olympus America, Medtronic, Boston Scientific Corporation, are at the vanguard of this sector, competitive Submucosal Lifting Agent Market, companies are strategically aligning themselves with the evolving needs of gastrointestinal healthcare. Intense focus on research and development to enhance the efficacy and safety of lifting agents has become a hallmark of competitive intelligence. Market players keenly observe technological advancements and novel ingredient formulations to stay ahead. Acquisitions and partnerships are common tactics to broaden product portfolios and expand geographical reach. Understanding competitors' product pipelines, regulatory compliance, and customer feedback forms the core of competitive intelligence, allowing companies to navigate the market dynamics effectively.

Business strategies in the Submucosal Lifting Agent Market involve a combination of innovation, market penetration, and strategic collaborations. Companies are investing heavily in research to develop cutting-edge formulations with improved biocompatibility and lifting capabilities. Emphasis on obtaining regulatory approvals swiftly is crucial, ensuring a competitive edge in the market. Moreover, strategic partnerships with healthcare institutions and endoscopy centers are facilitating the incorporation of lifting agents into routine clinical practices.

Key Recent Developments

New Product Launch

AscentX Medical is a startup founded in 2008. They developed minimally invasive endoscopic injection procedures for the treatment of different medical conditions. The G25 bulking agent is for the treatment of Gastroesophageal reflux disease.

Market Impact: This development promises to revolutionize treatment approaches, indicating a transformative leap in addressing medical conditions with enhanced precision, potentially reshaping the landscape of the Submucosal Lifting Agent Market.

October 2022, Boston Scientific's ORISE Gel Submucosal Lifting Agent, used in gastrointestinal endoscopic procedures, underwent a recall in several countries.

Market Impact: This event has instigated a ripple effect, impacting the market by raising concerns over product safety and regulatory compliance. The recall poses challenges for both the company and the market, underscoring the critical importance of stringent quality control measures in the Submucosal Lifting Agent industry.

Submucosal Lifting Agent Market Report Scope



Forecast Period

2023 to 2030

Historical Data Available for

2018 to 2022

Market Analysis

US$ Million for Value

Key Regions Covered

  • North America
  • Latin America
  • Europe
  • South Asia & Pacific
  • East Asia
  • The Middle East & Africa  

Key Countries Covered

  • United States
  • Canada
  • Germany
  • United Kingdom
  • France
  • Italy
  • Spain
  • Russia
  • China
  • Japan
  • South Korea
  • India
  • Thailand
  • Malaysia
  • Indonesia
  • Australia
  • New Zealand
  • GCC Countries
  • South Africa  

Key Market Segments Covered

  • Ingredient
  • Type
  • Application
  • End-use
  • Region

Key Companies Profiled

  • Laborie
  • Olympus America
  • Medtronic
  • Boston Scientific Corporation
  • Omnimed Ltd™
  • Micro-Tech Endoscopy
  • Ovesco Endoscopy AG

Report Coverage

  • Market Forecast
  • Company Share Analysis
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives  

Customization & Pricing

Available upon request

Submucosal Lifting Agent Market Research Segmentation

By Ingredient:

  • Poloxamer 188 and Polyoxyl-15-hydroxystearate
  • Gellan gum and Polysaccharide
  • Sodium Hyaluronate
  • Cellulose
  • Absorbable Starch Polymers
  • Poloxamers

By Type:

  • Normal saline
  • Dextrose water
  • Hydroxypropyl methylcellulose
  • Hydroxyethyl starch
  • Hyaluronic acid
  • Fibrinogen mixture
  • Succinylated gelatin
  • Eleview and ORISE gel

By Application:

  • Polyps
  • Adenomas
  • Early-stage Cancers
  • Gastrointestinal Mucosal Lesions
  • Others

By End-use:

  • Hospitals
  • Specialty Clinics
  • Surgical Centers
  • Others

By Region:

  • North America
  • Europe
  • East Asia
  • South Asia & Oceania
  • Latin America
  • Middle East & Africa

- Companies Covered in This Report -

  • Laborie


  • Olympus America

  • Medtronic

  • Boston Scientific Corporation

  • Omnimed Ltd™


  • Micro-Tech Endoscopy

  • Ovesco Endoscopy AG

- Frequently Asked Questions -

The market is anticipated to grow at a CAGR of 7.0% during the projected period.

The Submucosal Lifting Agent market was valued at USD 117.2 million in 2023.

The U.S. held the largest market share in 2023.

The prominent players in the market are Laborie, STERIS, Olympus America, Medtronic, Boston Scientific Corporation.

Specialty Clinics segment is expected to grow at the fastest growth during the forecast period.

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