CRBSI Treatment Market

Market Study on CRBSI Treatment: PMR Foresees a Host of Opportunities, Given the Rising Prevalence of Healthcare-associated Infections, Followed by Increasing Demand for Advanced Infection Control Measures

A Detailed Analysis of the CRBSI Treatment Market Based on the Continuous Innovation in Antimicrobial Therapies

Report ID: PMRREP33952

Number of Pages: 223

Format: PPT*, PDF, EXCEL

Industry: Healthcare

Published Date: January-2024

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CRBSI Treatment Market

The global CRBSI treatment market is forecast to expand at a CAGR of 5.7% and thereby increase from US$1.5 Bn in 2023, to US$2.2 Bn by the end of 2030.


Key Insights

CRBSI Treatment Market Size (2023E)

US$1.5 Bn

Projected Market Value (2030F)

US$2.2 Bn

Global Market Growth Rate (CAGR 2023 to 2030)


Historical Market Growth Rate (CAGR 2018 to 2022)


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Market Introduction and Definition

Catheter-related bloodstream infection (CRBSI) is a critical medical condition that results in systemic infections due to the invasion of microorganisms into the bloodstream via indwelling catheters. This occurs frequently when bacteria or fungi present on the surface of the catheter infiltrate the bloodstream, resulting in a spectrum of symptoms that can be severe enough to be fatal. To reduce the risks associated with CRBSI, it is critical to administer treatment in a timely and suitable manner. This may include removing or replacing the infected catheter, administering antibiotics, and providing supportive care to address potential complications.

Multiple variables influence the global CRBSI treatment market. A higher incidence of CRBSI is attributable to the increasing prevalence of chronic diseases necessitating long-term catheter use, the aging of the population, and the proliferation of invasive medical procedures and surgeries. In addition to a rise in healthcare expenditures, technological advances in catheter materials and designs drive the demand for effective CRBSI treatments. Additionally, the implementation of rigorous regulatory guidelines and a heightened awareness among healthcare professionals regarding infection control measures serve to further propel the market's expansion. Furthermore, the emphasis on the development of innovative antimicrobial coatings for catheters elevates the market environment.

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Market Growth Drivers

Rising Incidence of Chronic Illnesses that Require Extended Catheter Use

One of the primary factors propelling the global market for CRBSI treatment is the rising incidence of chronic illnesses that require extended catheter use. The global prevalence of chronic ailments, including cancer, kidney failure, and cardiovascular diseases, has led to a significant increase in the need for catheters to facilitate a wide range of medical interventions. Catheters are of paramount importance in the management of physiological parameters, medication administration, and fluid drainage, particularly in patients afflicted with chronic illnesses. Nevertheless, the extended duration of catheter insertion elevates the likelihood of CRBSI, underscoring the critical need for efficacious treatment approaches.

The increasing incidence of chronic illnesses is a complex factor that impacts the market for CRBSI treatments. Patients afflicted with ailments such as cancer frequently undergo chemotherapy, which necessitates the use of intravenous catheters to administer medication. In the same way, individuals afflicted with cardiovascular diseases may require catheters for procedures such as angioplasty, while those with kidney failure may require catheters for hemodialysis. The incidence of CRBSI cases is substantially influenced by the increase in the number of patients who require catheters for critical medical care, as these chronic diseases become more widespread. The prolonged catheterization observed in these specific patient populations emphasizes the critical nature of creating and implementing sophisticated CRBSI treatment approaches.

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Market Restraints

Emergence of Antibiotic-resistant Bacterial Strains

The global market for CRBSI treatments is significantly constrained by the emergence of antibiotic-resistant bacterial strains. The proliferation and improper utilization of antibiotics have contributed to the emergence of bacterial strains that exhibit resistance to traditional antibiotic therapies. The management and treatment of CRBSI are thus significantly complicated, as the efficacy of conventional antibiotics is compromised. Treatment of CRBSI is complicated by antibiotic resistance, which restricts the therapeutic options available. Due to the diminished effectiveness of widely used antibiotics, medical practitioners are compelled to utilize more potent and specialized antimicrobial agents, which frequently incur additional expenses for treatment.

Increasing Incidence of Bacterial Infections

The economic pressures associated with the management of catheter-related bloodstream infections represent a formidable obstacle for the global CRBSI treatment market. Both direct and indirect expenses associated with the treatment of CRBSI substantially burden healthcare systems and individual patients financially. Direct costs comprise expenditures associated with hospitalization, diagnostic examinations, potential surgical procedures, and antimicrobial treatments.

On the other hand, indirect costs incorporate elements such as extended hospital stays, productivity losses, and enduring healthcare consequences. The economic ramifications of CRBSI are especially complex due to their persistence beyond the initial phase of treatment. Extended hospitalization and the requirement for specialized care not only contribute to heightened healthcare costs but also place a burden on healthcare resources, which may result in interruptions to services and compromised quality of care for patients in other domains.


Rising Prevalence of Sophisticated Technologies, and Advancements in Catheter Construction

An advantageous factor propelling the expansion of the worldwide CRBSI treatment market is the rising prevalence of sophisticated technologies and advancements in catheter construction and materials. The continuous progression of medical technology has enabled the creation of catheters that possess improved antimicrobial characteristics and diminished susceptibility to infections. Catheters are currently integrating sophisticated materials, including silver nanoparticles, antimicrobial coatings, and other biocompatible substances, to establish a barrier that inhibits microbial colonization.

By addressing the urgent requirement for efficient treatment of CRBSI, the implementation of cutting-edge technologies also enhances catheter safety and patient outcomes. For example, antimicrobial coatings reduce the risk of catheter infections by releasing agents that inhibit bacterial growth on the surfaces of the catheters. Moreover, the incorporation of intelligent technologies, including sensors and indicators, facilitates the continuous surveillance of catheter-related parameters in real-time. This empowers the expeditious identification of potential complications and intervention.

These developments not only augment the effectiveness of treatment for CRBSI but also elevate the standard of care, fostering the welfare of patients and alleviating the financial strain linked to extended hospitalizations and complications. The CRBSI treatment market is currently experiencing a notable upswing in research and development endeavors that seek to develop catheters that not only fulfill their intended functions but also aid in the prevention of infections. This development is generating substantial prospects for expansion and advancement in the industry.

Analyst’s Viewpoint

The worldwide market for CRBSI treatment is anticipated to experience significant expansion, propelled by a convergence of factors that emphasize its importance within the wider healthcare domain. Catheters are increasingly utilized for medical interventions due to the rising prevalence of chronic diseases worldwide, including cancer, diabetes, and cardiovascular conditions. As a result, the incidence of catheter-related bloodstream infections (CRBSI) has increased. Consequently, there is an increasing need for efficacious remedies for CRBSI. Research and development efforts are being vigorously pursued by manufacturers in the CRBSI treatment market to introduce innovative and highly effective therapies.

The emphasis on the development of sophisticated catheter materials possessing antimicrobial characteristics, as well as the creation of highly effective antibiotics and antifungals, underscores the dedication to tackling the intricacies linked to CRBSI. Since the efficacy of CRBSI treatments has a substantial bearing on patient outcomes, the relationship between manufacturers and consumers is vital. Manufacturers must prioritize education initiatives, ongoing innovation, and product differentiation to establish and sustain a favorable relationship with healthcare providers and end-users. Additionally, stringent regulatory frameworks designed to guarantee the safety and efficacy of CRBSI treatments impact the market dynamics. Regulatory bodies across the globe play an active role in establishing benchmarks for the prevention of catheter-associated infections and approving novel therapeutic approaches. Manufacturers must strictly adhere to these regulations to successfully introduce their products to the market and establish credibility with healthcare professionals.

Supply-side Dynamics

The market for CRBSI treatments is dominated by major corporations including Novartis AG, Merck & Co., Inc., and Pfizer Inc. These pharmaceutical behemoths are at the forefront of antibiotic and antifungal agent development and distribution, which are critical for the treatment of CRBSI. The adoption of CRBSI treatments is most prevalent in North America, specifically the United States, due to its well-developed healthcare infrastructure and the significant prevalence of catheter-related infections. Hospitals in the United States are increasingly employing antifungals and antibiotics, including Vancomycin and echinocandins, to treat CRBSI cases. Europe, including countries such as Germany and the United Kingdom, makes substantial contributions to the adoption of CRBSI treatments, underscoring the global scope of this phenomenon.

Prominent entities in the CRBSI treatment industry are proactively influencing the terrain via strategic undertakings such as mergers, acquisitions, and partnerships. As an example, Pfizer maintains its commitment to research and development to develop new antimicrobial agents that exhibit improved effectiveness against CRBSI pathogens. To bolster their market presence, Merck and Novartis are concentrating on diversifying their product lines, incorporating cutting-edge technologies into the development of catheters, and forging strategic alliances. These entities are not solely exerting an impact on product developments but are also actively participating in educational initiatives and awareness campaigns aimed at increasing knowledge regarding the prevention and treatment of CRBSI. Their collaborative endeavors play a crucial role in stimulating market expansion and enhancing patient results worldwide.

CRBSI Treatment Market Segmentation

What Drug Class will be at the Forefront?

Vancomycin to be Dominant in Terms of Sales owing to their Effective Targeted Treatment

Antibiotics are anticipated to hold the most significant market share in the CRBSI treatment market, with vancomycin emerging as a major player. Vancomycin is a prevalent therapeutic agent utilized to address catheter-related bloodstream infections (CRBSIs) owing to its effective targeting of Gram-positive bacteria, which are frequently implicated in such infections. Its established efficacy and broad-spectrum activity establish it as a significant contributor to the antibiotics segment's market dominance.

It is expected that the echinocandin segment will experience the most rapid growth among the various CRBSI treatment markets. Echinocandins, including caspofungin and micafungin, demonstrate significant antifungal efficacy, specifically against Candida species, which are often associated with systemic infections that are catheter related. The escalating prevalence of fungal CRBSI instances, in conjunction with the effectiveness of echinocandins, is anticipated to propel the substantial expansion of this sector, rendering it a focal point for market innovation and expansion.

Which Test Kits Represent the Bestselling Category?

Injectables to be at the Forefront owing to Critical Functionality

It is expected that the injectable segment will hold the most significant market share in the CRBSI treatment industry. The prevalence of this condition can be ascribed to the critical nature of bloodstream infections associated with catheters, which frequently necessitate prompt and focused intervention. Antibiotics and antifungals, which are injectable, offer a rapid and direct pathway to treat systemic infections linked to CRBSI; thus, they are the treatment of choice across the board. Although the injectable segment is anticipated to retain a significant portion of the market, oral growth is anticipated to be the most rapid. Progress is being made in the development of oral formulations for the treatment of CRBSI, including antibiotics and antifungals.

Increased adoption is being propelled by the convenience of oral administration, particularly in less severe cases or during the transition from intravenous to oral therapy. This market segment is anticipated to experience substantial expansion due to the increasing variety and effectiveness of oral options. As a result, catheter-related bloodstream infections will have more adaptable and readily available treatment alternatives for both patients and healthcare providers.

Which Indications are Expected to Lead Globally?

Bacterial Infections Lead by Indication, Fungal CRBSI Cases on the Rise

It is anticipated that the bacterial infections segment will hold the most significant market share in the CRBSI treatment industry. Catheter-associated bloodstream infections often arise from bacterial pathogens; therefore, antibiotics assume a pivotal function in combating these infections. In conjunction with the established use of antibiotics, the high incidence of bacterial CRBSI establishes the bacterial infections segment as the market leader. The segment about fungal infections is projected to experience the most rapid growth among the various CRBSI treatment markets.

The prevalence of fungal CRBSI cases is on the rise, specifically among patients with compromised immune systems, which is driving an increased need for antifungal treatments. A growing awareness of fungal infections in the context of CRBSI and the development of novel antifungal therapies are propelling the fungal infection segment's explosive growth, establishing it as a pivotal area for market development and expansion.

Which is the Leading Distribution Channel?

Hospital Pharmacies to Accommodate the Largest Market Share

It is anticipated that hospital pharmacies will hold the most significant portion of the CRBSI treatment market. In the light of the critical nature of catheter-related bloodstream infections (CRBSIs), medical facilities frequently serve as the principal environments for their diagnosis, treatment, and management. As a result, hospital pharmacies fulfill a critical function by supplying patients with CRBSI with the essential medications and remedies required for their prompt and comprehensive care. It is anticipated that online pharmacies will experience the most rapid expansion in the CRBSI treatment market.

Progress towards virtual healthcare solutions is being propelled by the expanding utilization of digital platforms for healthcare services and the accessibility and convenience provided by online pharmacies. The increasing prevalence of telemedicine and online consultations is anticipated to drive a significant increase in demand for online pharmacies. This will create a burgeoning sector within the CRBSI treatment market and serve as an indication of the evolving trends in healthcare delivery.

Top Regional Markets

North America’s Lead Intact with Firmly Established Regulatory Frameworks, and Substantial Healthcare Expenditure

It is anticipated that North America will hold the largest market share of the worldwide CRBSI treatment market. Numerous elements contribute to this state of dominance. To begin with, North America is distinguished by its sophisticated healthcare infrastructure, firmly established regulatory frameworks, and substantial healthcare expenditures, all of which contribute to the extensive availability of state-of-the-art medical technologies and treatments. The region's vigorous research and development endeavors, with a particular emphasis on the US, sustain a competitive market environment by facilitating ongoing advancements in CRBSI treatments.

Furthermore, the correlation between an aging population and the high prevalence of chronic diseases in North America raises the probability of catheter utilization and, as a result, the occurrence of CRBSI. The region's significant emphasis on infection control protocols and the protection of patients serves to increase the need for efficacious treatments for CRBSI. In addition, healthcare professionals and patients in North America have a relatively high level of awareness regarding the risks associated with catheter-related infections; this has resulted in proactive measures being taken to prevent, diagnose, and treat such infections.

Rapidly Improving Access to Cutting-edge Medical Therapies to Create Tailwinds for Asian Markets

It is anticipated that East Asia will witness the most rapid expansion of the CRBSI treatment market. A multitude of factors contribute to this exponential growth. To begin with, nations such as China and Japan are witnessing advancements in healthcare infrastructure and access to cutting-edge medical therapies due to their growing healthcare expenditures. The rise in CRBSI cases can be attributed to the concurrent increase in the prevalence of chronic diseases caused by industrialization and urbanization in the region, which necessitate the use of catheters.

Moreover, the substantial and advancing age of the population in East Asia contributes to the increased need for CRBSI treatments. An upsurge in research and development endeavors within the region has resulted in the advent of novel technologies and therapies designed to treat CRBSI. In addition, the increasing recognition of the significance of prompt and efficacious treatment for healthcare-associated infections is exerting an impact on the market dynamics in East Asia. In addition, the adoption of advanced CRBSI remedies is being propelled by government initiatives to enhance healthcare standards and partnerships between regional and international healthcare organizations.

Competitive Intelligence and Business Strategy

Prominent entities in the CRBSI treatment industry, including Pfizer Inc., Merck & Co., Inc., and Novartis AG, are establishing a strategic foothold in the industry by focusing on product innovation, engaging in strategic partnerships, and conducting research and development. An essential tactic implemented by these prevailing entities is a steadfast dedication to the advancement of research and development. Considerable resources are allocated towards the exploration and advancement of innovative antibiotics and antifungal agents that demonstrate improved effectiveness against a wide range of pathogens responsible for CRBSI.

Through ongoing product pipeline expansion, these organizations strive to introduce state-of-the-art treatments, thereby securing a competitive advantage in the market and remaining at the forefront of emergent microbial threats. Their commitment to research and development not only enhances their current range of products but also positions them as frontrunners in spearheading advancements in the field of CRBSI treatment.

In order to enhance the stability of their market position, industry leaders are proactively participating in strategic alliances and cooperative ventures. Collaborations with other pharmaceutical companies, research institutions, or healthcare organizations may be a component of these alliances. These entities can expedite the development and commercialization of novel therapies and technologies by combining their resources and knowledge. Strategic collaborations additionally enable the formation of an international network, thereby guaranteeing a more extensive market penetration for their offerings and services, specifically in areas where CRBSI is prevalent.

CRBSI Treatment Market Report Scope



Forecast Period

2023 to 2030

Historical Data Available for

2018 to 2022

Market Analysis

US$ Million for Value

Key Regions Covered

  • North America
  • Latin America
  • Europe
  • South Asia & Pacific
  • East Asia
  • The Middle East & Africa  

Key Countries Covered

  • United States
  • Canada
  • Germany
  • United Kingdom
  • France
  • Italy
  • Spain
  • Russia
  • China
  • Japan
  • South Korea
  • India
  • Thailand
  • Malaysia
  • Indonesia
  • Australia
  • New Zealand
  • GCC Countries
  • South Africa  

Key Market Segments Covered

  • Drug Class
  • Route of Administration
  • Indication
  • Distribution Channel
  • Region

Key Companies Profiled

  • Aurobindo Pharma Limited
  • B. Braun Medical Inc.
  • Eli Lilly and Company
  • Fresenius SE & Co. KGaA
  • GSK plc
  • Merck & Co., Inc.
  • Mylan N.V. (Viatris)
  • Novartis
  • Pfizer Inc.
  • Sanofi AG
  • SteriMax Inc.
  • Teva Pharmaceutical Industries Ltd.

Report Coverage

  • Market Forecast
  • Company Share Analysis
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives  

Customization & Pricing

Available upon request

CRBSI Treatment Market Research Segmentation

By Drug Class:

  • Cloxacillin
  • Ceftazidime
  • Cefazoline
  • Daptomycin
  • Vancomycin
  • Teicoplanin
  • Echinocandin
  • Others

By Route of Administration:

  • Oral
  • Injectable

By Indication:

  • Bacterial Infections
  • Fungal Infection
  • Viral and Parasitic Infections

By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Drug Store
  • Online Pharmacies

By Region:

  • North America
  • Europe
  • East Asia
  • South Asia & Oceania
  • Latin America
  • Middle East & Africa

For report customisation and delivery information contact our sales representative.

Companies Covered in This Report

  • Aurobindo Pharma Limited
  • B. Braun Medical Inc.
  • Eli Lilly and Company
  • Fresenius SE & Co. KGaA
  • GSK plc
  • Merck & Co., Inc.
  • Mylan N.V. (Viatris)
  • Novartis
  • Pfizer Inc.
  • Sanofi AG
  • SteriMax Inc.
  • Teva Pharmaceutical Industries Ltd.

Frequently Asked Questions

The market is anticipated to grow at a CAGR of 5.7% during the projected period.


The CRBSI treatment market was valued at US$1.5 billion in 2023.

The US held the largest market share in 2023


The prominent players in the market are Aurobindo Pharma Limited, B. Braun Medical Inc., Eli Lilly and Company, and Fresenius SE & Co. KGaA.



The online pharmacies segment is expected to grow at the fastest rate during the forecast period.

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