Cell Free Protein Expression Market

Global Market Study on Cell Free Protein Expression: Continuous Flow Expression System Segment Expected to Account for a Higher Market Share Between 2016 and 2024

Cell Free Protein Expression Market Segmented By E.coli, Rabbit Reticulocytes, Wheat Germ, Insect Cells, Mammalian, Consumables Cell-free Protein Expression System in Enzyme Engineering, Protein Labeling, Protein-Protein interaction, Protein Purification

  • December-2016
  • PMRREP12385
  • 145 Pages
  • Healthcare
  • PPT, PDF, WORD, EXCEL

Market Overview

Cell-free protein expression (also known as in vitro translation, In vitro protein expression, cell-free translation, or cell-free protein synthesis) as the name suggests is the production of recombinant proteins in cell lysates rather than within cultured cells. Cell free protein expression uses the biomolecular machinery with all the components extracted from the desired cell type.

Cell free protein production can be done using various kinds and species of cell lysates, and these methods have numerous benefits and features over traditional in vivo methods. The global cell free protein expression market has been segmented on the basis of product type, application, expression mode, end users, and regions.

The global cell free protein expression market is projected to expand at a CAGR of 6.0% during the forecast period in terms of value. Global cell free protein expression market value is expected to increase to US$ 268.4 million by the end of 2024.

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Companies

Company Profiles 

  • New England Biolabs
  • GeneCopoeia, Inc. 
  • Takara Bio Company
  • CellFree Sciences Co.,Ltd.
  • Thermo Fisher Scientific Inc.
  • Promega Corporation
  • Bioneer corporation
  • Cube biotech
  • biotechrabbit GmbH
  • Jena Bioscience GmbH
  • Others.

Factors influencing the global cell free protein expression market growth

Growth of the global cell free protein expression market is mainly driven by increasing R&D outsourcing by pharmaceutical and biotechnological companies, declining R&D productivity and patent cliff sales drop leading to increasing research intensity in the pharmaceutical sector and increasing expenditure on biosimilar development. Other factors driving cell free protein expression market are new and advanced applications, growing demand for simple and efficient protein production methods and rapid process/product development due to fewer steps.

However, low protein production, high cost and short reaction scale, lack of eukaryotic co- and post-translational modifications and inability to carry out humanized glycosylation patterns, are expected to restrain growth of the market over the forecast period. Focus on novel approaches and development of fast, reliable and cost-effective methods for industrial scale production of proteins from cell lysates will define the future landscape of cell free protein expression market.

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Global cell free protein expression market forecast by product type

Based on product type, the market has been segmented into E. coli cell-free protein expression system, rabbit reticulocytes cell-free protein expression system, wheat germ cell-free protein expression system, insect cells cell-free protein expression system, mammalian cell-free protein expression system, and consumables. Mammalian cell-free protein expression system segment is expected to be the most lucrative segment in the cell free protein expression market owing to increasing applications of mammalian cell lysate in human antibody development studies.

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Global cell free protein expression market forecast by application

Based on the major applications, the market has been segmented into enzyme engineering, protein labelling, protein-protein interaction, and protein purification. Protein-protein interaction segment currently accounts for the highest revenue of the cell free protein expression market owing to the robust research and development initiatives related to protein libraries generation.

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Global cell free protein expression market forecast by expression mode

Based on expression mode, the cell free protein expression market is segmented into continuous flow expression and batch expression system. Continuous flow expression system is expected to account for the higher share for cell free protein expression market over the forecast period.

Global cell free protein expression market forecast by end user

Based on major end users, the cell free protein expression market is segmented into biotechnological companies, pharmaceutical companies, contract research organizations, and academic/research institutes. Academic/research institutes followed by contract research organizations are expected to account for the highest share for cell free protein expression market over the forecast period. Increasing outsourcing by pharmaceutical and biotechnological companies is expected to drive the cell free protein expression market in contract research organizations.

Global cell free protein expression market forecast by region

The global cell free protein expression market has been segmented into five major regions: North America, Latin America, Europe, Asia Pacific (APAC), and Middle East & Africa (MEA). In terms of value, North America is estimated to be the dominant market for global cell free protein expression market in 2016 owing to robust research and development infrastructure.

The Europe cell free protein expression market is expected to register a CAGR of 5.9% over the forecast period. Asia Pacific is estimated to be the fastest growing market in terms of CAGR. North America cell free protein expression market is expected to register a CAGR of 5.8% over the forecast period.

cell free protein expression market

Key market players dominating the global cell free protein expression market

Some key players in the global cell free protein expression market identified in this report are Thermo Fisher Scientific, Takara Bio, Inc., New England Biolabs, Promega Corporation, CellFree Sciences Co., Ltd., biotechrabbit GmbH, Bioneer Corporation, Cube Biotech GmbH, Jena Bioscience GmbH, and GeneCopoeia, Inc.  The report also identifies company-specific strategies related to product development; market consolidation initiatives and analysis of their specific strengths, weaknesses, opportunities, and threats.

Thermo Fisher Scientific is the leading providers of cell-free protein expression system accounting about 25% of market share in 2015. Promega Corporation is the second highest revenue generating company accounted for 14% revenue share in overall cell free protein expression market. Takara Bio, Inc. holds around 10% of market share in overall market. The company offers wide range of product under cell free protein expression category such as human cell-free protein expression system which is used in protein purification, protein labelling and high-throughput proteomic studies.

Market Segmentation

Key Segments Covered

  • By Product Type
    • E.coli Cell-free Protein Expression System
    • Rabbit Reticulocytes Cell-free Protein Expression System
    • Wheat Germ Cell-free Protein Expression System
    • Insect Cells Cell-free Protein Expression System
    • Mammalian Cell-free Protein Expression System
    • Consumables
      • Labelling Tags
      • Vectors
  • By Application
    • Enzyme Engineering
    • Protein Labeling
    • Protein-Protein interaction
    • Protein Purification
  • By Expression Mode
    • Continuous flow Expression
    • Batch Expression
  • By End User
    • Biotechnological Companies
    • Pharmaceutical Companies
    • Contract Research Organizations
    • Academic/ Research Institutes

Key Regions/Countries Covered

  • North America
  • Latin America
  • Europe
  • Asia Pacific (APAC)
  •  Middle East & Africa

 

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