D-Mannose Market

Market Study on D-Mannose: Demand Set to Surge from Animal Feed Industry

D-Mannose Market Powder, Capsules and Tablets Form in Functional Food, Dietary Supplements, Pharmaceuticals, Animal Feed

Market Snapshot

By value, Persistence Market Research has projected 4.2% CAGR for the global D-Mannose market for 2021 to 2031, with the market ending up at a valuation of close to US$ 5.5 Bn by 2031. As per projections, emerging markets in all regions are expanding at high CAGRs; however, North America is projected to hold around 33% of the global market value share for D-mannose through 2031.

D-Mannose Market Value (2020A)

US$ 3.5 Bn

Projected Sales of  D-Mannose (2031F)

US$ 5.5 Bn

Value CAGR (2021-2031)


Value Share of Top 5 Countries (2020A)


Find Out More about the Report Coverage


  • Nestle Health Science
  • NOW Health Group, Inc.
  • Pfanstiehl, Inc.
  • Vibrant Health
  • Hänseler AG
  • Source Naturals, Inc.
  • DuPont de Nemours, Inc.
  • Bio-Tech Pharmacal
  • Jarrow Formulas Inc.
  • Nutraceutical International Corporation
  • GNC Holdings, Inc.
  • Swanson Vitamins
  • Sweet Cures
  • VWR Lab Products Private Limited
  • NutriScience Innovations LLC

2016-2020 D-Mannose Consumption Analysis Vs Market Outlook for 2021-2031

The global market for mannose has shown considerable growth at a CAGR of 3.5% from 2016-2020. The market for D-glucose is racing ahead due to its rising demand as a natural alternative for antibiotics for the treatment of urinary tract infections. With a reduced body’s immune system and weak defense against germs, prevalence of urinary infection among the population is increasing, thus stimulating the growth of the global D-Mannose market size.

At the global level, D-mannose and D-fructose are high in demand from the North American region, followed by Europe. Demand from these regions is expected to grow due to increasing awareness and acceptance of low-calorie foods and natural alternatives for antibiotics.

Overall, global D-mannose consumption is projected to increase at a CAGR of 4.2% through 2031.

Customize this Report

Explore Intelligence Tailored to Your Business Goals.

Will Growing Preference for Prebiotics Drive D-Mannose Demand?

Prebiotic substances have a variety of health benefits, including constipation relief, gut microbial balance, reduced abdominal pain, and bloating prevention. The gut microflora transforms prebiotic nutrients into Short-Chain Fatty Acids (SCFAs), which nourish colon cells and have numerous health advantages. As a result, consumer demand for prebiotics has risen.

D-Mannose is considered to be prebiotic, as consumption of the same stimulates and fosters the growth of good bacteria in the digestive tract. D-Mannose is a very effective prebiotic element since it is not utilized for energy and most of the eaten amount is filtered through the kidneys and routed to the bladder for fast excretion.

  • DM Pharma, an India-based pharmaceutical company, offers D-Mannose accompanied by cranberry and hibiscus extracts, which have prebiotic properties, for women, to aid in maintaining urinary tract health.

Market Research Methodology - Perfected through Years of Diligence

A key factor for our unrivaled market research accuracy is our expert- and data-driven research methodologies. We combine an eclectic mix of experience, analytics, machine learning, and data science to develop research methodologies that result in a multi-dimensional, yet realistic analysis of a market.

Get actionable insights on Ship Repair And Maintenance Services Market

How is Growing Demand for Dietary Supplements Benefitting D-Mannose Manufacturers?

Low micronutrient intake is a serious public health concern, as it makes individuals more prone to infections and disorders. This, in turn, has resulted in increased consumption of dietary supplements and low calories foods such as D-Mannose for supporting urinary tract health.

Several studies published in prominent scientific journals have looked into the benefits of certain diets in maintaining a healthy urinary system. Consumers around the world, however, are failing to meet the required nutritional consumption levels due to changes in lifestyle and eating habits.

Opportunity for key D-Mannose providers for increasing their sales exists with growing penetration and awareness about dietary supplements that improve urinary tract health. Increasing prevalence of different chronic urinary infections among women and bladder problems marks an opportunity for new D-Mannose manufacturers to enter this market and meet the needs of consumers.

Explore Persistence Market Research’s expertise in promulgation of the business !

Why is There Increasing Use of D-Mannose in Animal Feed Being Witnessed?

D-Mannose manufacturing companies are shifting their focus to broadening applications and introducing products that can be used in a variety of industries, allowing them to capture both, domestic and foreign markets with the same product line. D-Mannose is a natural food ingredient that is increasingly being utilized in animal feed to enhance bladder health.

Inclusion of D-Mannose in animal food reduces the symptoms of feline cystitis, water infections, and other bladder disorders, and it can be used to prevent or cure bladder problems in animals as well. In mice, rats, horses, chickens, dogs, cats, guinea pigs, rabbits, and other animals, D-mannose serves to prevent bacteria from adhering to the membranes or cell walls.

D-Mannose's properties make it beneficial in personal care and cosmetics for its moisturizing, anti-aging, and anti-inflammatory properties. As a result, portfolio diversification is possible, resulting in greater sales opportunities for manufacturers of D-mannose.d-mannose-market

Which Factors are Restraining D-Mannose Market Growth?

Antibiotics are commonly prescribed to treat Urinary Tract Infections (UTIs), and the type and duration of the prescription is determined by the patient's health and the type of bacteria present in the urine. Despite the obvious side effects of antibiotics, patients prefer them to natural options that do not provide immediate results.

D-Mannose has proven to be effective against UTIs but not for complicated cystitis. Thus, increasing use of antibiotics for quickly and effectively eliminating infections is expected to hamper sales of D-mannose to some extent.

  • In July 2016, FDA recommendations suggested that the fluoroquinolone class of drugs used to cure UTIs must be reserved for more serious infections. Due to their powerful effects, fluoroquinolones are anticipated to account for a large share in the UTI treatment market.

Bloating and loose diarrhea are common side effects of D-Mannose use. Furthermore, D-Mannose can operate as a sperm receptor site on the zona pellucida during human fertilization, and it should not be used during pregnancy or breastfeeding. D-mannose has also been linked to kidney damage when taken in large amounts.

D-Mannose brands assure the safety of their products and no scientific results regarding D-Mannose side effects have been proven, but the possibility of side-effects is expected to restrict the number D-mannose consumers.

Country-wise insights

Why is the U.S. One of the Leading Markets for D-Mannose in the World?

The United States dominates the North America D-mannose market with the highest market volume share of 91.2%, owing to increased awareness among consumers for preventive health and wellness, coupled with the region being home to key manufacturers of D-mannose.

North America is also one of the progressive regions when it comes to replacing sugar with natural food alternatives. Rising market share for this region is due to an increase in demand for low-calorie food products as well as increase in the number of consumers suffering from lifestyle disorders such as diabetes, obesity, and cardiovascular disease.

The U.S. market for D-mannose is expected to reach close to US$ 1.5 Bn valuation by 2031.

Which Country Holds the Largest Market Share for D-Mannose in South Asia?

India holds the highest share in the South Asia market for D-mannose, owing to increased use of natural alternatives for antibiotics in end-use industries. This has provided several D-mannose suppliers with lucrative opportunities in the country. The market share of India in the South Asian region is around 44.5%.

Category-wise insights    

Which Form of D-Mannose is Most Demanded in the Global Market?

On the basis of form, D-mannose capsules & tablets are most demanded in the global market. Some companies such as NOW Health Group, Bio-Tech Pharmacal, and Source Naturals Inc. are providing D-mannose in capsules and tablets as they are convenient to intake as compared to D-mannose powder. Capsules & tablets hold a share of 51.4% in the global market.

How is Proliferation of the Dietary Supplements Industry Offer Growth Opportunities to D-Mannose Suppliers?

D-Mannose is a naturally occurring simple sugar that is found in fruits such as cranberries, blueberries, and pineapples as well as in other plants and fungi. When D-Mannose is ingested, it is quickly absorbed in the upper portion of the gastrointestinal tract, but very little of the sugar is metabolized. It, therefore, does not affect blood sugar levels, which makes it safe for diabetic patients.

Moreover, diabetes can be a potent cause of UTI infections. This factor has led to the emergence of D-Mannose as a solution for both the related diseases, thus driving D-mannose intake.

Growing consumer preference for low-carbohydrate food due to the prevalence of various diseases is resulting in increasing demand for such products, thus prompting D-mannose producing companies to introduce new and innovative functional food products in the market.

D-Mannose market value in the dietary supplements industry is US$ 1.46 Bn at present.

Competitive Dashboard:

Key players in the global market for carubinose are inclined at investing extensively in expansion, innovation, and R&D processes, and make use of advanced technology to gain a competitive advantage through the highest quality products. D-mannose producers also striving to improve their operational and innovative capabilities.

  • In 2018, Nestle Health Sciences opened the Nestlé Product Technology Center in Bridgewater, New Jersey for innovating new products. This center would allow the company to further strengthen its commitment to harnessing the power of nutrition for empowering customers’ lives.
  • In 2019, DuPont de Nemours, Inc.’s subsidiary DuPont Nutrition & Biosciences opened a new research office in the Netherlands. The new facility would enable the company to reach high sustainability standards along with improved research for further development.
  • In 2017, VWR International, LLC set up an innovation center in Bridgewater. This innovation center is a technology-driven research and collaboration environment, which was set up to closely work with its customers and solve their bioprocessing problems.

D-Mannose Industry Report Scope



Forecast period


Historical data available for


Market analysis

USD Million for Value

Key regions covered

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • The Middle East & Africa

Key countries covered

  • U.S.
  • Canada
  • Germany
  • U.K.
  • France
  • Italy
  • Spain
  • Russia
  • China
  • Japan
  • South Korea
  • India
  • Thailand
  • Malaysia
  • Indonesia
  • Australia
  • New Zealand
  • GCC Countries
  • Turkey
  • Northern Africa
  • South Africa

Key market segments covered

  • Form
  • End Use
  • Distribution Channel
  • Region

Key companies profiled

  • Nestle Health Science
  • NOW Health Group, Inc.
  • Pfanstiehl Inc
  • Vibrant Health
  • Hanseler AG
  • Source Naturals
  • DuPont de Numerous, Inc.
  • Bio-Tech Pharmacal
  • Jarrow Formulas
  • Nutraceutical International Corporation
  • GNC Holdings, Inc.
  • Swanson Vitamins
  • Sweet Cures
  • VWR Lab Products Private Limited
  • NutriScience Innovations LLC

Report coverage

  • Market Forecasts
  • Company Share Analysis
  • Competition Intelligence
  • DROT Analysis
  • Market Dynamics and Challenges
  • Strategic Growth Initiatives

Customization & pricing

Available upon request

D-Mannose Industry Research by Category


  • D-Mannose Powder
  • D-Mannose Capsules & Tablets

End Use

  • D-Mannose for Functional Food
  • D-Mannose for Dietary Supplements
  • D-Mannose for Pharmaceuticals
  • D-Mannose for Animal Feed
  • Others

Distribution Channel

  • Business to Business Sales of D-Mannose
  • Business to Consumer Sales of D-Mannose
    • Hypermarkets/Supermarkets
    • Specialty Stores
    • Online Retail

Media Release

- FAQs -

The global D-mannose market is currently valued at over US$ 3.6 Bn.

Demand drivers of D-mannose its use as an effective prebiotic agent, it aids in urinary tract health, channel proliferation in the dietary supplement industry, increasing demand for functional foods, and rising necessity for diabetic-friendly products across regions.

From 2016 to 2020, D-mannose consumption increased at a CAGR of 3.5%.

Sales of D-mannose are projected to increase at 4.2% CAGR and be valued at close to US$ 5.5 Bn by 2031.

GNC Holdings, Inc., DuPont de Numerous Inc., Bio-Tech Pharmacal, Nestle Health Sciences, NOW Health Group Inc., and VWR International LLC are the top 5 D-mannose manufacturers accounting for around 25% to 35% market share.

The market for D-mannose in Europe is led by Germany, followed by the U.K.

The U.S., China, Germany, India, and U.K. are the major demand centers for D-mannose.

The D-mannose industry in South Korea is set to surge at a CAGR of 6.6%, while that in India at a CAGR of 7.3% through 2031.


Oregano Oil Market

Global Market Study on Oregano Essential Oil - check its market share, size, revenue, latest trends, consumption, key players, regional outlook, competitive landscape & forecast.

Hydrolyzed Plant Protein Market

Hydrolyzed Plant Protein Market is expected to reach approximately US$ 1600 Mn by the end of 2019 in terms of value, and is estimated to reach US$ 2600 Mn by the end of 2029..

Industrial Fat Fraction Market

Industrial Fat Fraction Market is expected to witness a CAGR of 2.7% from 2017 to 2025. The market was worth US$ 10, 596.5 Mn in 2017 and is expected to touch a valuation of US$ 13,139.8 Mn by the end of 2025..

Moringa Ingredients Market

Global moringa ingredients market is currently valued at US$ 6.6 Bn, and is anticipated to expand at a healthy CAGR of 7.1% to top US$ 13.1 Bn by 2031.

Our Clients

Our Clients