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Blood clotting accelerants are used to enhance the process of blood clotting within a shorter period of time than it would require normally. Blood clotting is a complex mechanism which involves various factors and normal coagulation functioning in a patient is screened by tests prior to surgeries.
The use of blood clotting accelerant is increasing in clinical spheres as a result of increasing incidence of conditions like hemophilia, anemia, thrombolysis, pulmonary embolism (PE), deep vein thrombosis (DVT), liver diseases, surgical treatments and genetically inherited deficiencies which impede normal coagulation process and can be confirmed via blood clotting accelerants.
According to the National Hemophilia Foundation, von Willebrand disease affects up to 1% of US population. Current gene therapy research trials are focused on methods to insert factor VIII genes into hemophilic patients to restore normal coagulation functioning.
According to the clinicaltrials.gov data, together DVT and PE affect 500,000 people in Europe every year. This results in expensive disease treatment costs, days lost from work and represents the most common cause of deaths in hospitals.
The data reveals that out of total 2292 clinical trials on thrombosis, 392 clinical trials are currently in phase IV due to research funding from various governments, industrial entities, academic institutes and contract research organizations.
The stringent norms in public sector armed forces require medical test which includes blood testing where blood clotting accelerant are utilized to shorten the turnaround time of the screening. The recent trend of universal insurance coverage makes it obligatory to test blood to decide on the amount of premium and is mostly carried out through clinical laboratories using blood clotting accelerants.
Athletes and sportsperson undergo doping test intermittently before major events and since 2018, Tour de France has mandated at least 8 anti-doping tests per day to assess the presence of any performance boosting drugs in the body.
