SDS Poly Acrylamide Gel Electrophoresis Market

SDS Poly Acrylamide Gel Electrophoresis Market Outlook (2023 to 2033)

The Global revenue from the SDS Poly Acrylamide Gel Electrophoresis Market was around US$ 467.1 Million in 2022, with the global market expected to grow at a CAGR of 5.3% to reach a valuation of around US$ 827.2 Million by the end of 2033.

As analysed by Persistence Market Research, gels held a market share of around 57.3% in the global market, in 2022. The global SDS poly acrylamide gel electrophoresis market holds nearly 21.2% revenue share of the global electrophoresis market valued at US$ 2.2 Billion in 2022

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Sales Analysis of Market from 2014 to 2022 Vs Market Outlook for 2023 to 2033

The global market recorded a historic CAGR of 5.2% in the last 8 years from 2014 to 2022.

Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) is a methodology that is used for separating or sorting the proteins according to their molecular weight. This technique is commonly practised in various departments such as biochemistry, genetics, molecular biology, and biotechnology.

The primary factors that are driving the expansion of the SDS-PAGE market include the rising investment in research & development activities and the rise in the protein quantification research projects. It is also anticipated that increasing government financing and investment in the biotech sector will accelerate market expansion. The market for SDS-PAGE is anticipated to rise as a result of an increase in biopharmaceutical businesses and the development of biosimilar medicines. But will be constrained by a lack of qualified lab specialists and a high cost.

This process requires a lot of time and labour and can produce a lot of hazardous waste. Automated protein size and relative quantification have been performed using an integrated instrument; high-throughput platform. This factor can hamper the SDS-PAGE market.

The global market is likely to show high growth over the coming years at a CAGR of 5.3% and reach a global market size of 827.2 Million by 2033.

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How Can the Global Market for SDS Poly Acrylamide Gel Electrophoresis Grow?

“Rising Use of SDS-PAGE in Western Blotting, Advancements in Stain Free Gels”

A common technique for identifying target proteins is using western blotting while the main objective of SDS-PAGE is to separate the proteins according to their molecular weight. Technological advancements in the western blotting techniques in last decade has been occurred.

• For instance, according to the article titled " Evolving methodologies of western blotting for protein purification and analysis of protein " that was published in Futur J Pharm Sci 7, 2021, the introduction of western blotting tools (Pierce Fast) and streamlined procedures (Western Workflow) Rad's opened the door to making western blotting faster and more assessable. As a consequence, the demand for SDS-PAGE is also increasing.

SDS-PAGE is recommended for Western blotting over other techniques like native PAGE because it coats the hydrophobic area of the protein with its negative charge, counteracting the protein's total positive charge and allowing the protein to migrate towards the positive electrode. In contrast to native PAGE, which separates proteins according on their charge to molecular mass ratio, the proteins in the sample can therefore be resolved according to their molecular mass.

Technological advancement in stain free gels for better visualization is driving the market. Conventional staining techniques typically take a long time since they require the use of protein stains like Coomassie Brilliant Blue (CBB), silver, zinc, or other fluorescent dye-based stains. The technology for stain-free gels has advanced, making it possible to visualise and quantify proteins with greater sensitivity and improved dynamics. Stain –free gels obtain their activation properties when examined under UV light after electrophoresis for detection of protein samples. Stain free gels have proven to detect protein samples as minute as 20–50 ng, which is a lower detection range than some Coomassie blue stains.

This in turn provides a tremendous growth for SDS polyacrylamide gel electrophoresis market leaders to invest and manufacture new strain free based technology gels for expanding their business in SDS-PAGE.

In particular, when an individual has asthma, inhaling SDS can cause a number of acute problems such as wheezing, coughing, chest tightness, and shortness of breath. As a result, manufacturers are concentrating on creating products that are trustworthy and safe to use, which is driving the market's expansion and giving lucrative opportunities to the market.

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Can the Market Growth Be Affected in Any Way?

“Lack of Innovation Along with Precise Alternatives Like Flow Cytometry”

Electrophoresis is a highly precise and efficient analytical tool, but it should be improved in terms of electrophoresis run time, resolution, and automation.

Capillary electrophoresis is one technique that has shown significant improvements in terms of resolution and thus can be used to separate amphoteric molecules such as proteins. Furthermore, SDS polyacrylamide gel electrophoresis necessitates a large starting sample, which limits its application in protein purification. In such cases, techniques such as flow cytometry and immunohistochemistry are used to assess protein expression on a cell-by-cell basis.

Denaturation of proteins is another element posing a challenge to the market. The key component of SDS-PAGE is the intentional decomposition of proteins before electrophoresis. Generally, proteins extracted by SDS-PAGE cannot be assessed for catalase activity, protein binding connections, identification of protein cofactors, etc. To isolate native proteins for studies of structure-function connections, alternative techniques must be used. The blue-native PAGE method is one such alternative.

Such alternative methods may lower the demand for the SDS-PAGE, which can hamper the market.

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Country-wise Insights

Why is the United States Market Booming?

“Investments in Research and Development and Presence of Key Players”

The United States accounted for around 31.3% market share in the global market in 2022.

It is projected that the country's demand for SDS-PAGE will continue to outpace investment in research and development and the significantly expanding protein quantification research programmes.

Increased government financing for proteomics research initiatives is an additional characteristic. In addition, the United States Department of Health and Human Services will spend $40 million to enhance bio-manufacturing's contribution to the production of antibiotics, active pharmaceutical ingredients (APIs), and the crucial raw materials required to combat pandemics and generate necessary drugs.

Another factor that contributes to the country's excellent market is the presence of leading SDS-polyacrylamide gel electrophoresis manufacturers and their highly competent sales teams.

Will Germany Be a Lucrative Market for SDS Poly Acrylamide Gel Electrophoresis?

“Robust and Expanding Clinical Research by Manufactures”

The Germany market held around 5.0% share of the global market in 2022.

The advanced medical knowledge and easy access to equipment make Germany a desirable location for outsourcing clinical research. For instance, ICON plc announced in November 2021 that the Accellacare Site Network for clinical research has enlarged in reach and capabilities via a strategic alliance with six research sites across the country. The Accellacare Site Network's growth improves access to and interaction with investigative sites and patients, facilitating quicker hiring and cutting down on the overall time and expense of drug development for clients.

Thus, the above mentioned reason is expanding the product availability which increase the demand for SDS poly acrylamide gel electrophoresis.

How is China Emerging as a Prominent Market?

“Increasing Funding in Research and Development”

China held a market share of about 4.8% of the global market in 2022.

United States Government Accountability Office reports that from FY 2015 to 2021, federal agencies directly contributed $28.9 million to Chinese firms for research and development activities. For instance, China received funding from the National Institutes of Health and the Centers for Disease Control and Prevention for research on vaccines and drugs. Scientific articles, data collection systems, and international workshops were produced as a result of this funding.

Research and development investments have been a key factor in China's productivity growth despite the considerable labour and capital market distortions highlighted in the literature on Chinese economic development.

Thus, the above mentioned factor is facilitating the market to grow.

Category-wise Insights

Which Product is in Greater Demand On the Global Market?

“Less Time Consuming for Preparation with Ease to Handle.”

Gels held around 57.3% share of the total market in 2022.

The ease of accessing such gels through online portals has increased customer convenience, assisting in the growth of the demand for gels. Furthermore, advancements in chemical process research, such as electrophoresis, which includes precast gels, in addition to increased demand for much less time-consuming product manufacturing, will increase demand for the gels.

When an electric current is applied to the gel, molecules can pass through a permeable matrix that resembles a sieve. Because of this, gels are becoming increasingly significant in electrophoresis.

Which End User is Widely Adopted the SDS-PAGE?

“Rising Need for SDS-PAGE in Clinical Trials”

Clinical research held around 42.7% share of the total market in 2022.

Globally, clinical trials for protein assessment are increasing, which will increase demand for SDS-PAGE and cause it to dominate the clinical research segment.

• According to the WHO's clinical trials register, North America and Europe had the most clinical trials as of June 2021.
• The United States had registered more than 30% of clinical trials by February 2022. Decentralized clinical trials are also becoming more common, with a projected increase of more than 25% by 2022.

As a result of the decentralisation of clinical trial components, the number of clinical trials conducted each year has increased significantly. Rising clinical trials will boost the growth of SDS-PAGE market.

Competition Landscape

There are several significant competitors in the SDS polyacrylamide gel electrophoresis industry. To strengthen their positions in the market, the leading companies perform various strategic activities so that they are aware of the current ongoing market trends. Variety of techniques, including partnerships, joint ventures, product launches are being considered by the leading players to strengthen their position in the market.

Some key instances of development include:

• Promega has announced in 2020, its tabletop capillary electrophoresis (CE) instrument, the Spectrum Mini CE System, developed in conjunction with Hitachi High-Tech.
• The new CALX8 Reagent for life science laboratory scientists was released in August 2022, by Amerigo Scientific, who specializes in providing goods and services to the biomedical and life science communities. In molecular biology research procedures such protein purification, cell lysis, electrophoresis, and immunoassays, this reagent is widely employed.

Similarly, the team at Persistence Market Research has tracked recent developments related to companies in the SDS Poly Acrylamide Gel Electrophoresis market, which are available in the full report.

SDS Poly Acrylamide Gel Electrophoresis Industry Report Scope

Key Segments Covered in SDS Poly Acrylamide Gel Electrophoresis Industry Research

Product:

• Instruments
• Reagents
• Gels
  • Handcast Gels
  • Precast Gels

End User:

• Clinical Research
• Biotechnology and Pharmaceutical Industry
• Government Agencies
• Academic Institutes

Region:

• North America
• Latin America
• Europe
• South Asia
• East Asia
• Oceania
• Middle East and Africa