Nonalcoholic steatohepatitis is a syndrome causes liver damage develops in the individuals who are not alcoholic. The primary mechanisms of nonalcoholic steatohepatitis are obesity, glucose intolerance, metabolic stress, inflammation, dyslipidemia and fibrosis. Nonalcoholic steatohepatitis can develop into cirrhosis and liver cancer. For the diagnosis of the nonalcoholic steatohepatitis, liver biopsy, imaging procedures and various types of blood tests including complete blood count, fasting blood sugar, liver enzyme tests etc. are required. The common nonalcoholic steatohepatitis treatment may include weight loss, type-2 diabetes treatment, a decrease of obesity etc. However, many drugs have been tested for the nonalcoholic steatohepatitis treatment only a few drugs such as vitamin E and pioglitazone showed a positive effect. Other drugs such as ursodeoxycholic acid, metformin, statins, orlistat and pentoxifylline showed only partially positive results. In the last several years the nonalcoholic steatohepatitis is continuously increasing in both developed and emerging countries. According to the “National Health and Nutrition Examination Survey,” the proportion of Nonalcoholic fatty liver disease among chronic liver diseases increased from 47% to 75% between 1988 and 2008 in the United States (US). The major elements that can be considered for the pathological protagonists of nonalcoholic steatohepatitis are oxidative stress, altered lipid metabolism adipose and pancreas tissues, bile acids, gut microbiota, bacterial endotoxins, and systemic chronic inflammation. However, more clinical studies and drug approvals by regulatory authorities are very much essential for nonalcoholic steatohepatitis treatment during forecast periods.
The nonalcoholic steatohepatitis treatment market can be segmented by drug types, test types and end-user.
Based on the drug types the nonalcoholic steatohepatitis treatment market can be segmented as
Based on the test types the nonalcoholic steatohepatitis treatment market can be segmented as
Based on the end-user the nonalcoholic steatohepatitis treatment market can be segmented as
Increasing incidents of obesity due to unhealthy diets and weight gain promotes the nonalcoholic steatohepatitis syndrome which drives the nonalcoholic steatohepatitis treatment market. Increasing prevalence of type 2 diabetes, obesity and dyslipidemia lead to nonalcoholic steatohepatitis disease, which drives the nonalcoholic steatohepatitis treatment market. However, the unavailable of the Food and Drug Administration (FDA) approved drugs for the nonalcoholic steatohepatitis treatment restrains the growth of the nonalcoholic steatohepatitis treatment market.
Due to the increasing prevalence of obesity, high cholesterol and type-2 diabetes the nonalcoholic steatohepatitis treatment market are expected high growth during forecasting periods. Unhealthy lifestyles, no exercises causes nonalcoholic steatohepatitis syndrome which will grow the nonalcoholic steatohepatitis treatment market. However, because of the unavailability of FDA approved drugs and medications expected to restrain the nonalcoholic steatohepatitis treatment market during forecast periods.
North America is expected as the largest regional market share in the nonalcoholic steatohepatitis treatment market due to the presence of more number of market players, increasing awareness about nonalcoholic steatohepatitis treatment and marketing activities in the region followed by Europe. The nonalcoholic steatohepatitis treatment market is expected to grow fastest in the Asia Pacific may because of the increasing prevalence of obesity, high cholesterol and type-2 diabetes thus boosting the market growth. However, in the South Asian countries such as India and China, the opportunities to manufacture and distribute new nonalcoholic steatohepatitis treatment drugs is expected to be higher due to large population and increasing incidence of type-2 diabetes and obesity during forecasting periods.
Some of the Key Market Players operating in the nonalcoholic steatohepatitis treatment market are Allergan Inc., Galmed Pharmaceuticals Ltd., GENFIT, Gilead Sciences, Inc., Intercept Pharmaceuticals, Zydus and Cadila among others.
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