Global Market Study on 3D Cell Culture: Asia to Witness Highest Growth by 2020


  • Published On : Jul-2015 |
  • Pages : 91 Pages |
  • Format :

3D cell culture is a man-made environment which is created to allow cells to grow and interact with the surroundings in all three dimensions. It is an advanced cell culture technique that overcomes limitations of 2D cell culture in terms of cellular characteristics and behavior. 3D cell culture is better suited to study disease models by cellular modeling different disease states. Research laboratories and institutes, hospitals, and biopharmaceutical and biotechnology companies are adopting 3D cell culture for better outputs and the adoption rate is posed to increase rapidly in the near future. Rising investment in 3D cell culture development, increasing research related activities, rising demand for organ transplantation, and 3D cell culture’s ability to replace animal in research and pharmaceutical testing drive growth of the 3D cell culture market. However, budgetary constraints faced by small and medium-sized laboratories and lack of consistency in 3D cell culture products are key restraints for the market.

Europe dominates the 3D cell culture market. The U.K. represents the largest market for 3D cell culture in the region. This is due to rising investment in 3D cell culture market, increasing research related activities, and 3D cell culture’s ability to replace the animal in research and pharmaceutical testing.

This report provides in-depth analysis and estimation of the 3D cell culture market for the period 2014–2020, considering 2013 as the base year for calculation. Data pertaining to current market dynamics, including market drivers, restraints, trends, opportunities, and strategic developments has been provided in the report. The 3D cell culture market is categorized on the basis of technology, application, the end user, and geography. On the basis of technology, the 3D cell culture market is segmented into extracellular matrices or scaffolds, bioreactors, gels, scaffold-free platforms, and microchips. 

In terms of applications, the market is segmented into research, drug discovery, tissue engineering, clinical applications, and stem cell biology. On the basis of the end user, the market comprises research laboratories and institutes, biotechnology and pharmaceutical industries, hospitals and diagnostic centres, and others. In the geographical analysis, the report identifies and analyses market size and forecast for North America, Europe, Asia and Rest of the World (RoW).

3D cell culture refers to a process of growing cell culture in a 3D environment. It provides a 3D view of the cells grown which helps to analyze cell culture in a better way. 3D cell culture accurately stimulates normal cell morphology, proliferation, differentiation, and migrations and thus, is better suited to study disease models by cellular modeling different disease states. Globally, the 3D cell culture market is witnessing significant growth due rising investments by major players in the market, increasing research related activities, and rising demand for organ transplantation. Moreover, 3D cell culture’s ability to replace the animal in research and pharmaceutical testing is also driving the growth of the market. However, factors such as budgetary constraints faced by small and medium-sized laboratories and lack of consistency in 3D cell culture products are restraining the growth of the global 3D cell culture market. The global 3D cell culture market was valued at US$ 586.1 Mn in 2014 and is projected to expand at a CAGR of 29.1% to account for US$ 2,717.6 Mn by 2020.

Europe has the largest market for 3D cell culture. Extracellular matrices or scaffolds are the largest segments in the overall 3D cell culture market. On the basis of the end user, biotechnology and biopharmaceutical industries dominate the 3D cell culture market. The Europe 3D cell culture market was valued at US$ 234.4 Mn in 2014 and is expected to account for US$ 1,067.8 Mn by 2020 at a CAGR of 28.7%. One of the latest trends that have been observed in the 3D cell culture market is increasing usage of laboratory automation for 3D cell culturing.

Some of the major players in the 3D cell culture market are Sigma-Aldrich Corporation, Thermo Fisher Scientific, Inc., Corning Incorporated, and Becton, Dickinson and Company, 3D Biotek LLC, Lonza Group, 3D Biomatrix, Inc.

3d-cell-cultures-market

Some of the major players in the 3D cell culture market:

  • Sigma-Aldrich Corporation.
  • Thermo Fisher Scientific, Inc.
  • Corning Incorporated.
  • Becton.
  • Dickinson and Company.
  • 3D Biotek LLC.
  • Lonza Group.
  • 3D Biomatrix, Inc.
  • InSphero AG.
  • Reinnervate Ltd.
  • Global Cell Solutions, Inc.

These key market players have been profiled on the basis of attributes such as company overview, products and services, recent developments, growth strategies, sustainability and financial overview.

Chapter 1 Preface 9

1.1 Report Description 9

1.2 Research Methodology 10

1.3 Assumptions 10

Chapter 2 Market Synopsis 11

Chapter 3 Porter’s Five Forces Analysis 13

Chapter 4 Market Overview 16

4.1 Market Definition 16

4.2 Market Drivers 19

      4.2.1 Rising investments 19

      4.2.2 Increasing research related activities 19

      4.2.3 Ability to replace animal in research and pharmaceutical testing 20

      4.2.4 Rising need for organ transplantation 20

4.3 Impact Analysis of Market Drivers 22

4.4 Market Restraints 23

      4.4.1 Budgetary constraints 23

      4.4.2 Lack of consistency in products 23

4.5 Impact Analysis of Market Restraints 23

4.6 Market Opportunities 24

      4.6.1 Use of microfluidic technology 24

      4.6.2 Increasing focus on regenerative medicine 25

4.7 Market Trends 25

      4.7.1 Increasing use of automation 25

Chapter 5 Global Market Size and Forecast 26

Chapter 6 Market Size and Forecast by Technology 34

6.1 Extracellular Matrices or Scaffolds 34

6.2 Bioreactors 36

6.3 Gels 38

6.4 Scaffold-free Platforms 40

6.5 Microchips 42

Chapter 7 Market Size and Forecast by Application 45

7.1 Research 45

7.2 Drug development and testing 47

7.3 Tissue engineering 49

7.4 Clinical application 51

7.5 Stem cell biology 53

Chapter 8 Market Size and Forecast by End User 56

8.1 Research Laboratories and Institutes 56

8.2 Biotechnology and Pharmaceutical Industries 58

8.3 Hospitals and Diagnostic Centers 60

8.4 Others 62

Chapter 9 Market Size and Forecast by Geography 63

9.1 North America 63

9.2 Europe 65

9.3 Asia 68

9.4 Rest of the World (RoW) 71

Chapter 10 Competitive Scenario 72

10.1 Competitive Benchmarking 72

Chapter 11 Company Profiles 74

11.1 Becton, Dickinson and Company 74

      11.1.1 Company overview 74

      11.1.2 Products and services 74

      11.1.3 Financial performance 75

      11.1.4 Key developments 75

11.2 Corning Incorporated 76

      11.2.1 Company overview 76

      11.2.2 Products and services 76

      11.2.3 Financial performance 77

      11.2.4 Key developments 77

11.3 Lonza Group 77

      11.3.1 Company overview 78

      11.3.2 Products and services 78

      11.3.3 Financial performance 78

      11.3.4 Key developments 79

11.4 Thermo Fisher Scientific, Inc. 79

      11.4.1 Company overview 80

      11.4.2 Products and services 80

      11.4.3 Financial performance 80

      11.4.4 Key developments 81

11.5 3D Biotek LLC 82

      11.5.1 Company overview 82

      11.5.2 Products and services 82

      11.5.3 Financial performance 83

      11.5.4 Key developments 83

11.6 3D Biomatrix, Inc. 83

      11.6.1 Company overview 83

      11.6.2 Products and services 84

      11.6.3 Financial performance 84

      11.6.4 Key developments 84

11.7 Global Cell Solutions, Inc. 84

      11.7.1 Company overview 84

      11.7.2 Products and services 85

      11.7.3 Financial performance 85

      11.7.4 Key developments 85

11.8 InSphero AG 85

      11.8.1 Company overview 85

      11.8.2 Products and services 86

      11.8.3 Financial performance 86

      11.8.4 Key developments 86

11.9 Sigma-Aldrich Corporation (A subsidiary of Merck KGaA) 86

      11.9.1 Company overview 87

      11.9.2 Products and services 87

      11.9.3 Financial performance 87

      11.9.4 Key developments 88

11.10 Reinnervate Ltd (A subsidiary of ReproCELL) 88

      11.10.1 Company overview 89

      11.10.2 Products and services 89

      11.10.3 Financial performance 89

      11.10.4 Key developments 90


List of Tables

TABLE 1 Drivers for 3D cell culture market: Impact analysis 22

TABLE 2 Restraints for 3D cell culture market: Impact analysis 23

TABLE 3 Global 3D cell cultures market size, by region, 2010 – 2013 (US$ Mn) 26

TABLE 4 Global 3D cell cultures market size, by region, 2014 – 2020 (US$ Mn) 27

TABLE 5 Global 3D cell cultures market size, by technology, 2010 – 2013 (US$ Mn) 28

TABLE 6 Global 3D cell cultures market size, by technology, 2014 – 2020 (US$ Mn) 29

TABLE 7 Global 3D cell cultures market size, by applications, 2010 – 2013 (US$ Mn) 30

TABLE 8 Global 3D cell cultures market size, by applications, 2014 – 2020 (US$ Mn) 31

TABLE 9 Global 3D cell cultures market size, by end user, 2010 – 2013 (US$ Mn) 32

TABLE 10 Global 3D cell cultures market size, by end user, 2014 – 2020 (US$ Mn) 33

TABLE 11 Global 3D cell culture extracellular matrices or scaffolds market size, by region, 2010 – 2013 (US$ Mn) 35

TABLE 12 Global 3D cell culture extracellular matrices or scaffolds market size, by region, 2014 – 2020 (US$ Mn) 36

TABLE 13 Global bioreactors market size, by region, 2010 – 2013 (US$ Mn) 37

TABLE 14 Global bioreactors market size, by region, 2014 – 2020 (US$ Mn) 38

TABLE 15 Global gels market size, by region, 2010 – 2013 (US$ Mn) 39

TABLE 16 Global gels market size, by region, 2014 – 2020 (US$ Mn) 40

TABLE 17 Global scaffold-free platforms market size, by region, 2010 – 2013 (US$ Mn) 41

TABLE 18 Global scaffold-free platforms market size, by region, 2014 – 2020 (US$ Mn) 42

TABLE 19 Global microchips market size, by region, 2010 – 2013 (US$ Mn) 43

TABLE 20 Global microchips market size, by region, 2014 – 2020 (US$ Mn) 44

TABLE 21 Global 3D cell culture research market size, by region, 2010 – 2013 (US$ Mn) 46

TABLE 22 Global 3D cell culture research market size, by region, 2014 – 2020 (US$ Mn) 47

TABLE 23 Global drug development and testing market size, by region, 2010 – 2013 (US$ Mn) 48

TABLE 24 Global drug development and testing market size, by region, 2014 – 2020 (US$ Mn) 49

TABLE 25 Global tissue engineering market size, by region, 2010 – 2013 (US$ Mn) 50

TABLE 26 Global tissue engineering market size, by region, 2014 – 2020 (US$ Mn) 51

TABLE 27 Global clinical application market size, by region, 2010 – 2013 (US$ Mn) 52

TABLE 28 Global clinical application market size, by region, 2014 – 2020 (US$ Mn) 53

TABLE 29 Global stem cell biology market size, by region, 2010 – 2013 (US$ Mn) 54

TABLE 30 Global stem cell biology market size, by region, 2014 – 2020 (US$ Mn) 55

TABLE 31 Global research laboratories and institutes market size, by region, 2010 – 2013 (US$ Mn) 57

TABLE 32 Global research laboratories and institutes market size, by region, 2014 – 2020 (US$ Mn) 57

TABLE 33 Global biotechnology and pharmaceutical industries market size, by region, 2010 – 2013 (US$ Mn) 59

TABLE 34 Global biotechnology and pharmaceutical industries market size, by region, 2014 – 2020 (US$ Mn) 59

TABLE 35 Global hospitals and diagnostic centers market size, by region, 2010 – 2013 (US$ Mn) 60

TABLE 36 Global hospitals and diagnostics centers market size, by region, 2014 – 2020 (US$ Mn) 61

TABLE 37 North America 3D cell culture market size, by country, 2010 – 2013 (US$ Mn) 64

TABLE 38 North America 3D cell culture market size, by country, 2014 – 2020 (US$ Mn) 65

TABLE 39 Europe 3D cell culture market size, by country, 2010 – 2013 (US$ Mn) 67

TABLE 40 Europe 3D cell culture market size, by country, 2014 – 2020 (US$ Mn) 68

TABLE 41 Asia 3D cell culture market size, by country, 2010 – 2013 (US$ Mn) 70

TABLE 42 Asia 3D cell culture market size, by region, 2014 – 2020 (US$ Mn) 71

TABLE 43 Major categories and products of BD Biosciences 74

TABLE 44 Major product categories of Corning, Inc. 76

TABLE 45 Major product segments of Lonza Group 78

TABLE 46 Major product segments of Thermo Fisher Scientific, Inc. 80

TABLE 47 Major product and service segments of 3D Biotek LLC 82

TABLE 48 Major product segments of 3D Biomatrix, Inc. 84

TABLE 49 Major product segments of Global Cell Solutions, Inc. 85

TABLE 50 Major product segments of InSphero AG 86

TABLE 51 Major product segments of Sigma-Aldrich Corporation 87

TABLE 52 Major product segments of Reinnervate Ltd 89


List of Figures 

FIG. 1 3D cell cultures market: Porter’s five forces analysis 13

FIG. 2 Methods for 3D cell culture 17

FIG. 3 Major end users of 3D cell culture market 18

FIG. 4 Global 3D cell cultures market share, by region, by value, 2013 26

FIG. 5 Global 3D cell cultures market share, by technology, by value, 2013 28

FIG. 6 Global 3D cell cultures market share, by applications, 2013 30

FIG. 7 Global 3D cell cultures market share, by end user, 2013 32

FIG. 8 Global 3D cell culture extracellular matrices or scaffolds market share, by region, by value, 2013 34

FIG. 9 Global bioreactors market share, by region, by value, 2013 37

FIG. 10 Global gels market share, by region, by value, 2013 39

FIG. 11 Global scaffold-free platforms market share, by region, by value, 2013 41

FIG. 12 Global microchips market share, by region, by value, 2013 43

FIG. 13 Global 3D cell culture research market share, by region, by value, 2013 46

FIG. 14 Global drug development and testing market share, by region, by value, 2013 48

FIG. 15 Global tissue engineering market share, by region, by value, 2013 50

FIG. 16 Global clinical application market share, by region, by value, 2013 52

FIG. 17 Global stem cell biology market share, by region, by value, 2013 54

FIG. 18 Global research laboratories and institutes market share, by region, by value, 2013  56

FIG. 19 Global biotechnology and pharmaceutical industries market share, by region, by value, 2013 58

FIG. 20 Global hospitals and diagnostic centers market share, by region, by value, 2013  60

FIG. 21 North America 3D cell culture market share, by country, by value, 2013 64

FIG. 22 Europe 3D cell culture market share, by country, by value, 2013 67

FIG. 23 Asia 3D cell culture market share, by country, by value, 2013 70

FIG. 24 Competitive landscape of ScarTreatment Market, 2014 72

FIG. 25 Becton, Dickinson and Company’s revenue and net income, 2012 – 2014 (US$ Mn)  75

FIG. 26 Corning, Inc.’s net sales and net income, 2012 – 2014 (US$ Mn) 77

FIG. 27 Lonza Group’s sales and net income, 2012 – 2014 (US$ Mn) 78

FIG. 28 Thermo Fisher Scientific, Inc.’s revenue and net income, 2012–2014 (US$ Mn) 80

FIG. 29 Sigma-Aldrich Corporation’s revenue and net income, 2012 – 2014 (US$ Mn) 87

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