Scientific investigations has been conducted on the role of microbes and their potential use in preventing and treating diseases. Microbiome is the multifarious assemblage of microorganisms, genes and their metabolites, inhabiting the human and animal mucosal sides, gastric tract and on the skin. It is known that the microbiome interacts with its host and thus assists in ingestion and detoxification, providing immunity, defending against pathogens, and sustaining a good health. Studies have revealed that healthy individuals are often colonized with different microbiomes than those suffering from various disease. It is used for maintaining good health both in humans and animals.
Microbiome Therapeutics (MBT) is a new age therapy that improves status of health by interacting with the human microbiome in a specific manner. In this technique, bacterial and other microorganism colonies in the gastrointestinal tract for managing serious health conditions like obesity, pre-diabetes and diabetes. MBT is also introduced for improving animal health like the Penn Vet Center for Host-Microbial Interactions (CHMI) is working on how microbes like viruses, parasites and bacteria’s are influencing health of animals. Researches are being conducted in Penn Vet on the role of microbiome on animal health and on diseases stretching from atopic dermatitis, inflammatory bowel disorder.
In human, Microbiome therapeutic (MBT) technique is playing a predominant role in improving heath. One of the key component of MBT product is probiotics. These are the non-digestible growth substrates, metabolic agents and co-factors that are specially used by beneficial bacteria already present in the digestive system but in less quantity. Hence, probiotics helps in increasing the population of health inducing bacteria at the expense of detrimental bacteria. The U.S National Institutes of Health sponsored Human Microbiome Project (HMP) is advancing in the human microbiome known as microbiota. This also creates metabolites that has variety of effects: producing toxins from foods, providing new nutrients and vitamins to the host body, enabling nutrients for other desirable microorganisms, metabolism of drugs. Probiotic drinks are available in the market, which contains Lactobacillus that is lactic bacteria, they increases the amount of good bacteria in the gut and thus helps to improve the health. These probiotic drinks aids in sustaining the intestinal flora and they has been evolving as a useful tool in improving symptoms of chronic disorder. However, their effectiveness is still questioned.
The global human microbiome market, microbiota can be divided on the basis of disease, product, dosage form and geography. The category diseases can be subdivided into allergic conditions, autoimmune diseases, cancer, diarrhea, diabetes and obesity. On the basis of products, it can be classified into probiotic drinks and food supplements. Geographical division mainly consists of North America, Asia Pacific, Europe, Latin America and Rest of the world.
Is it being expected that the European market will bloom in near future. This growth can be attributed to the rising incidences of stressful and uneven lifestyle, infections like diarrhea, throat and other autoimmune disorders. Asia is expected to be the second largest-growing region of the human microbiome market mainly because of high population density and improved lifestyle leading to increased buying power of the people are the major driving factors for this market. Moreover, recession hitting the western market, enabling the companies to focus on the Asian market to meet their revenue.
Some eminent of the key players in the global human microbiome market are AB-Biotics, Bayer HealthCare AG, Dannon, Cell biotech, Merck, Yakult, DuPont.